1166-34-3 Usage
Uses
Different sources of media describe the Uses of 1166-34-3 differently. You can refer to the following data:
1. Serotonin
inhibitor.
2. A 5-HT antagonist
Biological Activity
5-HT 2 antagonist.
Check Digit Verification of cas no
The CAS Registry Mumber 1166-34-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,6 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1166-34:
(6*1)+(5*1)+(4*6)+(3*6)+(2*3)+(1*4)=63
63 % 10 = 3
So 1166-34-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H24N2OS.ClH/c1-22(2)15-8-16-24-19-12-7-6-11-18(19)21-20(23)14-13-17-9-4-3-5-10-17;/h3-7,9-14H,8,15-16H2,1-2H3,(H,21,23);1H/b14-13+;
1166-34-3Relevant articles and documents
Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors
Yang, Qingang,Chen, Lili,He, Xuchang,Gao, Zhenting,Shen, Xu,Bai, Donglu
scheme or table, p. 1400 - 1405 (2009/09/29)
The severe acute respiratory syndrome (SARS) coronavirus 3CL protease is an attractive target for the development of anti-SARS drugs. In this paper, cinanserin (1) analogs were synthesized and tested for the inhibitory activities against SARS-coronavirus (CoV) 3CL protease by fluorescence resonance energy transfer (FRET) assay. Four analogs show significant activities, especially compound 26 with an IC50 of 1.06 μM.
