117068-45-8 Usage
General Description
1-(1-(2-hydroxyethoxy)-3-azidopropyl)thymine is a chemical compound commonly referred to as HET-TP. It is a thymidine analogue that contains an azido group, making it a potential building block for the synthesis of various nucleoside analogs. It has been studied for its potential applications in nucleic acid labeling, bioconjugation, and drug development. The hydroxyethoxy group attached to the azidopropyl chain allows for efficient coupling reactions with other biomolecules, making it a valuable tool in chemical biology and biotechnology research. Additionally, the thymine base provides an opportunity for nucleic acid recognition and binding, presenting opportunities for drug targeting and delivery.
Check Digit Verification of cas no
The CAS Registry Mumber 117068-45-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,0,6 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 117068-45:
(8*1)+(7*1)+(6*7)+(5*0)+(4*6)+(3*8)+(2*4)+(1*5)=118
118 % 10 = 8
So 117068-45-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H15N5O4/c1-7-6-15(10(18)13-9(7)17)8(19-5-4-16)2-3-12-14-11/h6,8,16H,2-5H2,1H3,(H,13,17,18)
117068-45-8Relevant articles and documents
Acyclic analogues of 3'-azido-3'-deoxythymidine as potential antiviral agents. Nucleoside synthesis by Michael addition
Scheiner,Geer,Bucknor,Imbach,Schinazi
, p. 73 - 76 (2007/10/02)
An acyclic derivative of 3'-azido-3'-deoxythymidine, (R,S)-1-[1-(2-hydroxyethoxy)-3-azidopropyl]thymine (2), has been synthesized by a path involving Michael-type addition. Related thymidine analogues lacking the C(3')-C(4') bond were similarly obtained.