118-62-7Relevant articles and documents
Efficient synthesis of 16-28 membered macrocyclic crown amides via ring closing metathesis
Ibrahim, Yehia A.,Behbehani, Haider,Ibrahim, Maher R.,Malhas, Rana N.
, p. 7273 - 7282 (2003)
Ring closing metathesis of suitable diamides containing 1,ω-dienes led to efficient synthetic approaches towards macrocylic polyoxadiamides 1-18 with 16-28 membered ring sizes in good to excellent yields using Grubbs' catalyst.
Electrochemical Chalcogenation of β,γ-Unsaturated Amides and Oximes to Corresponding Oxazolines and Isoxazolines
Baidya, Mrinmay,De Sarkar, Suman,Mahanty, Kingshuk,Maiti, Debabrata,Mallick, Samrat
supporting information, (2020/02/04)
The current report represents a transition-metal-free synthesis of oxazoline and isoxazoline derivatives by a tandem electro-oxidative chalcogenation-cyclization process. Both C?Se and C?S bond-forming protocols were developed without using any external oxidant and the reaction was performed at room temperature, open to the air. Using this methodology, 29 substituted oxazoline and 16 substituted isoxazoline derivatives were synthesized with up to 91% isolated yield. (Figure presented.).
