118807-85-5 Usage
General Description
1H-Benzimidazole-2-carbonitrile, 5-methoxy, 3-oxide, also known as 1-(5-methoxy-1H-benzimidazol-2-yl) ethanone, is a chemical compound with potential pharmacological properties. It is a derivative of benzimidazole, a heterocyclic compound commonly found in pharmaceutical drugs. This specific compound has a cyano group (carbonitrile) and a methoxy group attached to its benzimidazole ring, along with an oxide group at the 3rd position. The presence of these functional groups may give this compound potential as a drug entity, with potential applications in medicinal chemistry for developing new drugs with various biological activities. Further research and exploration are needed to fully understand the medicinal potential of 1H-Benzimidazole-2-carbonitrile, 5-methoxy, 3-oxide.
Check Digit Verification of cas no
The CAS Registry Mumber 118807-85-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,8,0 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 118807-85:
(8*1)+(7*1)+(6*8)+(5*8)+(4*0)+(3*7)+(2*8)+(1*5)=145
145 % 10 = 5
So 118807-85-5 is a valid CAS Registry Number.
118807-85-5Relevant articles and documents
o-Nitroaniline Derivatives. Part 9. Benzimidazole N-Oxides Unsubstituted at N-1 and C-2
Harvey, Ian W.,McFarlane, Michael D.,Moody, David J.,Smith, David M.
, p. 681 - 690 (2007/10/02)
Since previous routes to the title compounds (1) have proved unsatisfactory as general methods, a simple new synthesis has been devised.N-Cyanomethyl-o-nitroanilines (5) are cyclised in basic media, giving 2-cyanobenzimidazole N-oxides (12) in good yield.Hydrolysis of these products with hydrochloric acid gives, directly, the title compounds as their hydrochloride salts (13), which may be isolated and purified, and which give the free N-oxides (1) by treatment with aqueous ammonia followed by evaporation. o-Nitrophenylglycine esters (4) may satisfactorily replace the nitriles (5) in certain cases.A modification of this kind in the related nitropyridylglycine series leads to 3H-imidazolpyridine 1-oxide (20).