1193-72-2 Usage
Description
1-Bromo-2,4-dichlorobenzene is an aryl halide characterized by its colorless to light yellow crystalline mass. It can be distinguished from other bromodichlorobenzene isomers using infrared (IR) and Raman spectral data. 1-BROMO-2,4-DICHLOROBENZENE is known for its ability to undergo Suzuki–Miyaura cross-coupling reactions with arylboronic acids in the presence of various Suzuki catalysts, making it a versatile compound in organic chemistry.
Uses
Used in Organic Synthesis:
1-Bromo-2,4-dichlorobenzene is used as a key intermediate in organic synthesis for the production of various compounds. Its reactivity and structural properties make it a valuable building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Bromo-2,4-dichlorobenzene is used as a raw material and intermediate for the synthesis of various drugs. Its unique structure allows for the development of new medicinal compounds with potential therapeutic applications.
Used in Agrochemicals:
1-Bromo-2,4-dichlorobenzene is also utilized in the agrochemical industry as a starting material for the synthesis of pesticides and other agrochemical products. Its versatility in chemical reactions enables the creation of a wide range of compounds with different biological activities.
Used in Dye Industry:
In the dye industry, 1-Bromo-2,4-dichlorobenzene is employed as a crucial intermediate for the production of various dyes and pigments. Its chemical properties allow for the development of a diverse range of colorants with specific characteristics and applications.
Used in the Production of 2,4,4'-Trichloro-Biphenyl:
1-Bromo-2,4-dichlorobenzene is used to produce 2,4,4'-trichloro-biphenyl, which requires the use of aqueous sodium carbonate (Na2CO3) and solvents such as dioxane and ethanol. 1-BROMO-2,4-DICHLOROBENZENE has various applications in different industries, further highlighting the versatility of 1-bromo-2,4-dichlorobenzene as a starting material.
Check Digit Verification of cas no
The CAS Registry Mumber 1193-72-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1193-72:
(6*1)+(5*1)+(4*9)+(3*3)+(2*7)+(1*2)=72
72 % 10 = 2
So 1193-72-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H3BrCl2/c7-5-2-1-4(8)3-6(5)9/h1-3H
1193-72-2Relevant articles and documents
Kharasch,Legault,Sprowls
, p. 409,411 (1938)
PROCESS FOR THE PREPARATION OF ORGANIC HALIDES
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Paragraph 00143, (2017/08/01)
The present invention provides a halo-de-carboxylation process for the preparation of organic chlorides, organic bromides and mixtures thereof, from their corresponding carboxylic acids, using a chlorinating agent selected from trichloroisocyanuric acid (TCCA), dichloroisocyanuric acid (DCCA), or combination thereof, and a brominating agent.
Bromination by means of sodium monobromoisocyanurate (SMBI)
Okada, Yukihiro,Yokozawa, Masanori,Akiba, Miwa,Oishi, Kazuhiko,O-Kawa, Kyoji,Akeboshi, Tomohiro,Kawamura, Yasuo,Inokuma, Seiichi,Nakamura, Yosuke,Nishimura, Jun
, p. 2506 - 2511 (2007/10/03)
A variety of aromatic compounds with both activating and deactivating substituents were brominated with sodium monobromoisocyanurate (SMBI) 1, diethyl ether, diethyl ether-methanesulfonic acid, trifluoroacetic acid, or sulfuric acid were employed as solvents. Thus nitrobenzene was conveniently brominated in sulfuric acid, benzene was readily monobrominated in diethyl ether-methanesulfonic acid, and phenol was selectively brominated at the ortho position under mild conditions in refluxing diethyl ether. With substituents that are easily protonated, trifluoroacetic acid may be employed as solvent in the reaction with 1, in contrast NBS was ineffective in trifluoroacetic acid. This renders 1 a superior reagent relative to NBS. In addition to aromatics, alkenes, ketones and esters were also brominated with 1. Diethyl malonate was brominated with 1 and then subjected to a Bingel reaction with NaH to afford the desired methanofullerene in reasonable yield.
