1194-74-7

• 

• Basic information

  1. Product Name: 4(1H)-Pyrimidinone, 6-hydroxy-2,5-dimethyl- (9CI)
  2. Synonyms: 4(1H)-Pyrimidinone, 6-hydroxy-2,5-dimethyl- (9CI);6-Hydroxy-2,5-Dimethyl-4(1H)-Pyrimidinone;4(1H)-Pyrimidinone, 6-hydroxy-2,5-dimethyl-;4-hydroxy-2,5-dimethyl-1H-pyrimidin-6-one;4(3H)-PyriMidinone, 6-hydroxy-2,5-diMethyl-;2,5-diMethylpyriMidine-4,6-diol;2,5-dimethyl-4,6-dihydroxy-pyrimidine;dimethyl-4,6-dihydroxy-pyrimidine
  3. CAS NO:1194-74-7
  4. Molecular Formula: C6H8N2O2
  5. Molecular Weight: 140.13992
  6. EINECS: N/A
  7. Product Categories: PYRIMIDINE;alcohol
  8. Mol File: 1194-74-7.mol
  9. Article Data: 5

• Chemical Properties

  1. Melting Point: >360 °C
  2. Boiling Point: 302.5 °C at 760 mmHg
  3. Flash Point: 136.8 °C
  4. Appearance: /
  5. Density: 1.36 g/cm³
  6. Vapor Pressure: 0.000549mmHg at 25°C
  7. Refractive Index: 1.599
  8. Storage Temp.: Sealed in dry,Room Temperature
  9. Solubility: N/A
  10. PKA: 6.93±0.10(Predicted)
  11. CAS DataBase Reference: 4(1H)-Pyrimidinone, 6-hydroxy-2,5-dimethyl- (9CI)(CAS DataBase Reference)
  12. NIST Chemistry Reference: 4(1H)-Pyrimidinone, 6-hydroxy-2,5-dimethyl- (9CI)(1194-74-7)
  13. EPA Substance Registry System: 4(1H)-Pyrimidinone, 6-hydroxy-2,5-dimethyl- (9CI)(1194-74-7)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 1194-74-7(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

1194-74-7 Suppliers

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• 4(3H)-Pyrimidinone,6-hydroxy-2,5-dimethyl-

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• Pharmaceutical Grade CAS 1194-74-7 with competitive price

  Cas No: 1194-74-7

• USD $ 139.0-210.0 / Kilogram

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• 4(1H)-Pyrimidinone,6-hydroxy-2,5-dimethyl-

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• 2,5-Dimethylpyrimidine-4,6-diol

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• 4(1H)-Pyrimidinone, 6-hydroxy-2,5-dimethyl- (9CI) 1194-74-7

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• 2,5-dimethylpyrimidine-4,6-diol

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• 4(3H)-Pyrimidinone,6-hydroxy-2,5-dimethyl- CAS NO.1194-74-7

  Cas No: 1194-74-7

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1194-74-7 Usage

Uses

2,5-Dimethylpyrimidine-4,6-diol is a chemical reagent used in the synthesis of pharmaceutically active dimethylpyrimidines.

Check Digit Verification of cas no

The CAS Registry Mumber 1194-74-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1194-74:
(6*1)+(5*1)+(4*9)+(3*4)+(2*7)+(1*4)=77
77 % 10 = 7
So 1194-74-7 is a valid CAS Registry Number.

InChI:InChI=1/C6H8N2O2/c1-3-5(9)7-4(2)8-6(3)10/h1-2H3,(H2,7,8,9,10)

1194-74-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	4-hydroxy-2,5-dimethyl-1H-pyrimidin-6-one

1.2 Other means of identification

Product number	-
Other names	2,5-dimethyl-4,6-dihydroxy-pyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1194-74-7 SDS

1194-74-7Upstream product

• 609-02-9 methyl-malonic acid dimethylester 
• 124-42-5 acetamidine hydrochloride 
• 609-08-5 Diethyl methylmalonate 

1194-74-7Downstream Products

• 18260-92-9 6-chloro-2,5-dimethyl-pyrimidin-4-ylamine 
• 1780-33-2 4,6-dichloro-2,5-dimethyl-pyrimidine 

1194-74-7Relevant articles and documents

-

Hasapis,MacLeod

, p. 2087 (1979)

-

Pyrimidine Derivatives Which Are Antagonists Of Vitronectin Receptor

-

Page/Page column 14, (2010/11/30)

A subject of the invention is the compounds of formula (I); in which R1, R2, R3, R4 and R have the meanings indicated in the description, their preparation process, their use as medicaments having an antagonist activity on the vitronectin receptor and the pharmaceutical compositions containing them.

PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF

-

Page/Page column 173, (2008/06/13)

The present invention encompasses novel substituted pyrimidine compounds of Formula (I): which act as MCH receptor antagonists. These compounds are useful in pharmaceutical compositions whose use includes prophylaxis or treatment of improving memory function, sleeping and arousal, anxiety, depression, mood disorders, seizure, obesity, diabetes, appetite and eating disorders, cardiovascular disease, hypertension, dyslipidemia, myocardial infarction, binge eating disorders including bulimia, anorexia, mental disorders including manic depression, schizophrenia, delirium, dementia, stress, cognitive disorders, attention deficit disorder, substance abuse disorders and dyskinesias including Parkinson’s disease, epilepsy, and addiction.

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