1194-76-9 Usage
General Description
5-Chloro-6-hydroxy-2-MethylpyriMidin-4(3H)-one is a chemical compound also known as N-Methyl-5-chloro-6-hydroxy-4(3H)-pyrimidinone. It is a derivative of pyrimidine and is commonly used in pharmaceutical research as a starting material for the synthesis of antiviral and antifungal agents. 5-Chloro-6-hydroxy-2-MethylpyriMidin-4(3H)-one has potential applications in the development of new drugs due to its ability to inhibit viral and fungal enzymes. Additionally, it has been found to possess antifungal and antibacterial properties, making it a valuable compound in the field of medicinal chemistry. Its structure and properties make it a promising candidate for further research and potential therapeutic development.
Check Digit Verification of cas no
The CAS Registry Mumber 1194-76-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1194-76:
(6*1)+(5*1)+(4*9)+(3*4)+(2*7)+(1*6)=79
79 % 10 = 9
So 1194-76-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H5ClN2O2/c1-2-7-4(9)3(6)5(10)8-2/h1H3,(H2,7,8,9,10)
1194-76-9Relevant articles and documents
Ylides of Heterocycles. VII. . I-, N-, P- and S-Ylides of Pyrimidones
Habib, Nargues Samuel,Kappe, Thomas
, p. 385 - 388 (2007/10/02)
The reaction of pyrimidone derivatives 1a-d with iodosobenzene prepared in situ from diacetoxyiodobenzene or dichloroiodobenzene afforded the iodonium-ylides 2a-d in good yields.Their thermal rearrangement produced 5-iodo-4-phenoxy-pyrimidin-6(1H)-ones 3a-c.Reductive deiodination of 3 gave the corresponding 4-phenoxypyrimidin-6(1H)-ones 4a-c.Acid catalized treatment of the iodonium-ylides 2a-d with nucleophiles such as pyridine, nicotinamide, isoquinoline, or triphenylphosphine produced the corresponding N- or P-ylides 7, 8, 9, and 10, respectively.The thiophanium-ylides 11a,c were obtained from the iodonium-ylides 2 without the use of a catalyst.The pyridinium-ylides 7 have also been prepared from the 5-halopyrimidones 5 or 6 which in turn could be obtained from the reactive iodonium-ylides 2 with hydrochloric or hydrobromic acid, respectively.
