1199-99-1Relevant articles and documents
Energetics of Intramolecular Photoassociation in 3-Phenyl-1-(dimethylamino)propane in the Vapor Phase
Halpern, Arthur M.
, p. 6484 - 6489 (1984)
The photophysical properties of 3-phenyl-1-(dimethylamino)propane (I) are reported in the vapor phase under collision-free conditions.The absorption spectrum is interpreted as the sum of noninteracting phenyl and amino chromophores.Excitation at 265 nm (n
REDUCTION OF ACID AMIDES TO AMINES WITH SODIUM BOROHYDRIDE.
YAMADA,KIKUGAWA,IKEGAMI
, p. 394 - 396 (1965)
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Palladium-Catalyzed Cross-Coupling of Superbase-Generated C(sp3) Nucleophiles
Freure, Garrett P. R.,Lavertu, Jean-Danick E.,Newman, Stephen G.,Skrotzki, Eric A.
, p. 12258 - 12263 (2021/10/26)
A range of methods has been investigated recently for the arylation of weakly acidic C(sp3)-H bonds, primarily exploiting directed metalation with a transition metal catalyst or radical formation via hydrogen atom transfer. In this work, a classical base-mediated approach is taken, exploiting the ability of organometallic superbases to metalate very weakly acidic (pKa> 40) C-H bonds. Conditions are developed with eithern-BuLi/diamine orn-BuLi/KOtBu superbases to enable metalation to occur with high selectivity. Organolithium nucleophiles can be directly used in cross-coupling, or organozincs can be formed to enable reactions with functional group-dense organohalides.
Method for preparing tertiary amine organic compound by decomposing substituted formamide under mild condition
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Paragraph 0019-0021; 0049, (2021/06/13)
The invention discloses a method for preparing tertiary amine organic compounds by decomposing substituted formamide under mild conditions, which comprises the following steps: heating and stirring aldehydes serving as a reaction substrate, substituted formamide serving as a solvent, a reducing agent and an amination reagent, Ti-based oxide/hydroxide serving as a catalyst and a small amount of water serving as an auxiliary agent to generate the corresponding tertiary amine compound. Hydrogen is not needed in the reaction process. The method can be suitable for various aldehydes including aromatic aldehydes, fatty aldehydes and the like, and has the characteristics of high conversion rate and single product, and the tertiary amine compound can be simply, efficiently and safely synthesized without using hydrogen and noble metals in the reaction, so that the method has remarkable economic effects and application prospects.
