120298-37-5

• 

• Basic information

  1. Product Name: 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE
  2. Synonyms: 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE;4-Hydroxy-6-Methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonaMide
  3. CAS NO:120298-37-5
  4. Molecular Formula: C8H11NO3S3
  5. Molecular Weight: 265.37
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 120298-37-5.mol
  9. Article Data: 5

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: 1.661
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE(CAS DataBase Reference)
  10. NIST Chemistry Reference: 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE(120298-37-5)
  11. EPA Substance Registry System: 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE(120298-37-5)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 120298-37-5(Hazardous Substances Data)

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• 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE CAS 120298-37-5

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• 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE CAS:120298-37-5

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• 120298-37-5 5,6-DIHYDRO-4H-4-HYDROXY-6-METHYLTHIENO[2,3-B]THIOPYRAN-2-SULPHONAMIDE

  Cas No: 120298-37-5

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120298-37-5 Usage

General Description

5,6-Dihydro-4H-4-hydroxy-6-methylthieno[2,3-b]thiopyran-2-sulphonamide, often abbreviated as DHTT, is an organic compound whose structure features a thiopyran ring, which is a six-membered ring containing one sulphur atom and five carbon atoms. Its complex structure also consists of an additional sulphur atom bonded to an NH2 group, forming a sulfonamide. The compound also has a hydroxyl (OH) and a methyl (CH3) group. While this specific chemical is not commonly discussed or known in popular research, its components like thiopyrans and sulphonamides are significant in medicinal chemistry, often used in drug development due to their bioactive properties.

Check Digit Verification of cas no

The CAS Registry Mumber 120298-37-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,2,9 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 120298-37:
(8*1)+(7*2)+(6*0)+(5*2)+(4*9)+(3*8)+(2*3)+(1*7)=105
105 % 10 = 5
So 120298-37-5 is a valid CAS Registry Number.

InChI:InChI=1/C8H11NO3S3/c1-4-2-6(10)5-3-7(15(9,11)12)14-8(5)13-4/h3-4,6,10H,2H2,1H3,(H2,9,11,12)

120298-37-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120298-37-5 SDS

120298-37-5Upstream product

120298-37-5Downstream Products

• 154802-22-9 5,6-dihydro-4-hydroxy-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide 

120298-37-5Relevant articles and documents

Process for the preparation of 6-substituted-4-oxo-thieno [2,3b]thiopyran-2-sulfonic acid

-

Page/Page column 6, (2008/12/04)

The present invention relates to one-pot process for the preparation of 6-substituted-4-oxo-thieno[2,3b]thiopyran-2-sulfonic acid of formula (I), which comprises, reacting 2-thienylthiol with alkenyl acid in the presence of an aromatic hydrocarbon solvent and a base, cyclization of the resulting compound and further reacting with an acid anhydride and sulfuric acid to get the desired compound of formula (I). The compound of formula (I) is the key intermediate in the preparation of (S,S)-5,6-dihydro-4-alkyylamino-6-substituted-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide and analogs thereof.

Process for preparing 5,6-dihydro-4-(S)-(ethylamino)-6-(S) methyl-4H-thieno[2,3b]thiopyran-2-sulphonamide-7,7-dioxide HCI

-

Page/Page column 9, (2008/06/13)

The present invention relates to an improved process for the preparation of 5,6-dihydro-4-(S)-(ethylamino)-6-(S)methyl-4H-thieno[2,3b]thiopyran-2-sulphonamide-7,7-dioxide hydrochloride of formula (I) commonly known as Dorzolamide Hydrochloride useful as an agent to reduce intraoccular pressure by inhibiting carbonic anhydrase enzyme

Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use

-

, (2008/06/13)

Aromatic sulfonamides with a saturated heterocycle fused thereto are carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure.

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