120444-71-5 Usage
General Description
Deramciclane is a non-benzodiazepine class anxiolytic and antipsychotic drug that was formerly under investigation for medical use in schizophrenia and Alzheimer's disease. Chemically, it belongs to the ergoline family and is classified as serotonin antagonist and reuptake inhibitor. Furthermore, it exhibits effects on the dopamine and adrenergic receptor systems, which have been linked to its psychopharmacological profile. Trials had shown its potential in treating generalized anxiety disorders, but its clinical development was halted due to insufficient efficacy. As such, it is no longer actively researched or sold as a medicinal product.
Check Digit Verification of cas no
The CAS Registry Mumber 120444-71-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,4,4 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 120444-71:
(8*1)+(7*2)+(6*0)+(5*4)+(4*4)+(3*4)+(2*7)+(1*1)=85
85 % 10 = 5
So 120444-71-5 is a valid CAS Registry Number.
InChI:InChI=1/C20H31NO/c1-18(2)17-11-12-19(18,3)20(15-17,22-14-13-21(4)5)16-9-7-6-8-10-16/h6-10,17H,11-15H2,1-5H3/t17-,19-,20+/m1/s1
120444-71-5Relevant articles and documents
High purity (1R,2S,4R)-(-)-2-[(2′-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof
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Example 2, (2010/11/29)
The invention relates to high purity (1R,2S,4R)-(?)-2-[(2′-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2′-{N,N
