1209-71-8Relevant articles and documents
First enantioselective total syntheses and absolute configurations of 4,5-dioxo-seco-γ-eudesmol and 5β,11-dihydroxyiphionan-4-one, two aglycones of naturally occurring sesquiterpenes with new skeletons
Gao,Xiong,Zhou,Li
, p. 37 - 39 (2007/10/03)
A facile synthetic route to two new carbon skeleton sesquiterpenes 4,5-dioxo-seco-γ-eudesmol and 5β,11-dihydroxyiphionan-4-one from (+)-dihydrocarvone has been described. The configuration of the 5β,11-dihydroxyipbionan-4-one was confirmed by stereospecific synthesis.
Biotransformation of (+/-)-4,8-dimethylcyclodeca-3(E),7(E)-dien-1β-ol and (+)-Hedycaryol by Cichorium intybus
Piet, Dennis P.,Minnaard, Adriaan J.,Heyden, Karel A. van der,Franssen, Maurice C. R.,Wijnberg, Joannes B. P. A.,Groot, Aede de
, p. 243 - 254 (2007/10/02)
The biotransformation of the synthetic (E,E)-1,5-cyclodecadienol 5 and (+)-hedycaryol (11) by a root suspension of fresh chicory has been investigated.Incubation of 5 with a root suspension gave a 2:1 mixture of epimeric eudesmanediols 7a and 7b whereas 11 was selectively converted into cryptomeridiol (12).An explanation for the obtained results is proposed.
NEUROTROPHIC SESQUITERPENE-NEOLIGNANS FROM MAGNOLIA OBOVATA: STRUCTURE AND NEUROTROPHIC ACTIVITY
Fukuyama, Yoshiyasu,Otoshi, Yukio,Miyoshi, Kumi,Nakamura, Kazuhiko,Kodama, Mitsuaki,et al.
, p. 377 - 392 (2007/10/02)
Novel sesquiterpene-neolignans, eudesobovatols A (1) and B (2), eudesmagnolol (3), eudeshonokiols A (4) and B (5), clovanemagnolol (6), and caryolanemagnolol (7), have been isolated from the bark of Magnolia obovata.Their structures were elucidated to be sesquiterpenes (eudesmol, 4,4,8-trimethyltricyclo2,5>dodecane-1,9-diol, and clovanediol) combined through ether bond with neolignans such as obovatol, honokiol, and magnolol on the basis of spectral data, degradation, and/or synthesis.Compounds 1, 6, and 7 were found to exhibit interesting neurotrophic activity on a neuronal cell culture system derived from fetal rat hemisphere.
