121150-43-4Relevant articles and documents
Unusual rate enhancement of bimolecular dehydrocondensation to form amides at the interface of micelles of fatty acid salts
Kunishima, Munetaka,Imada, Hiroko,Kikuchi, Kanako,Hioki, Kazuhito,Nishida, Jin,Tani, Shohei
, p. 7254 - 7257 (2005)
(Chemical Equation Presented) Speeding up: A micelle-water interface acts as a suitable reaction field for dehydrocondensation. The coupling reaction of fatty acid salts with a triazine-type amphiphilic dehydrocondensing agent in a micellar system (see picture) underwent up to 2000-fold acceleration. The rate enhancement can be attributed to the higher local concentration and preorientation of the reactants in the micelles.
Method of inducing a phase transition of a bilayer membrane vesicle
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Page/Page column 16; 17, (2018/11/10)
Provided is a bilayer membrane vesicle capable of undergoing a phase transition. The bilayer membrane vesicle includes: (a) a fatty acid salt having 6 to 20 carbon atoms; (b) an alcohol or an amine compound having an aliphatic chain of 6 to 20 carbon atoms; and (c) an artificial synthetic lipid or a phospholipid capable of forming a bilayer membrane. Preferably, this bilayer membrane vesicle further contains (d) a tertiary amine as a component of the membrane. Also provided is a method of inducing a phase transition of a bilayer membrane vesicle, the method including the step of adding a dehydrating condensing agent or a dehydrating condensing agent precursor having the property of accumulating at an interface to the bilayer membrane vesicle. By causing the lipids that form a molecular aggregate to chemically change, it is possible to change the physical property and the morphology of the molecular aggregate and control the timing of phase transitions such as membrane fusion. In the membrane fusion, for example, fusion can occur without leakage of the contents of the bilayer membrane vesicle.
ANTIMICROBIAL COMPOUNDS AND METHODS OF USE
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Paragraph 0237; 0239, (2014/06/25)
The present disclosure provides antimicrobial compounds, compositions comprising such antimicrobial compounds, and methods of their use, in particular, antibacterial compounds and antifungal compounds. In certain aspects, the antimicrobial compounds are e