121905-60-0 Usage
General Description
M-Tolylmagnesium chloride, also known as 3-methylphenylmagnesium chloride, is a chemical compound that is commonly used as a reagent in organic synthesis. It is a Grignard reagent, which means it is a compound comprised of a magnesium atom bonded to a carbon containing a functional group, in this case a tolyl group. M-Tolylmagnesium chloride is a versatile compound that can be used in the formation of carbon-carbon bonds, as well as in the reduction of carbonyl compounds. It is often utilized in the pharmaceutical and fine chemical industries for the synthesis of complex organic molecules. As with all Grignard reagents, it must be handled and used with caution due to its reactivity and sensitivity to air and moisture.
Check Digit Verification of cas no
The CAS Registry Mumber 121905-60-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,9,0 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 121905-60:
(8*1)+(7*2)+(6*1)+(5*9)+(4*0)+(3*5)+(2*6)+(1*0)=100
100 % 10 = 0
So 121905-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H7.ClH.Mg/c1-7-5-3-2-4-6-7;;/h2-3,5-6H,1H3;1H;/q-1;;+2/p-1
121905-60-0Relevant articles and documents
Continuous preparation of arylmagnesium reagents in flow with inline IR monitoring
Brodmann, Tobias,Koos, Peter,Metzger, Albrecht,Knochel, Paul,Ley, Steven V.
experimental part, p. 1102 - 1113 (2012/08/27)
A newly developed microscale ReactIR flow cell was used as a convenient and versatile inline analytical tool for Grignard formation in continuous flow chemical processing. The LiCl-mediated halogen/Mg exchange reaction was used for the preparation of functionalized arylmagnesium compounds from aryl iodides or bromides. Furthermore, inline IR monitoring was used for the analysis of conversion and possible byproduct formation, as well as a potential tool for elucidation of mechanistic details. The results described herein indicate that the continuous flow systems are effective for highly exothermic reactions such as the Grignard exchange reaction due to fast mixing and efficient heat transfer.
