122-74-7Relevant articles and documents
Triphenylphosphine/germanium(IV) chloride combination: A new agent for the reduction of α-bromo carboxylic acid derivatives
Kagoshima, Hirotaka,Hashimoto, Yukihiko,Oguro, Dai,Kutsuna, Takaaki,Saigo, Kazuhiko
, p. 1203 - 1206 (1998)
The Ph3P/GeCl4 combination was found to be effective for the reduction of various α-bromo carboxylic acid derivatives. When a-bromo carboxylic acid derivatives were treated with Ph3P/GeCl4, the corresponding dehalogenated products were obtained in good to excellent yields. Moreover, selected carboxylic acid derivatives were dehalogenated even when a catalytic amount (0.2 equiv) of GeCl4 was employed in the presence of water (1.0 equiv). The present reduction was also applied to the selective half-reduction of an α,α-dibromo-β-lactam.
Scandium trifluoromethanesulfonate as an extremely active Lewis acid catalyst in acylation of alcohols with acid anhydrides and mixed anhydrides
Ishihara, Kazuaki,Kubota, Manabu,Kurihara, Hideki,Yamamoto, Hisashi
, p. 4560 - 4567 (2007/10/03)
Scandium trifluoromethanesulfonate (triflate), which is commercially available, is a practical and useful Lewis acid catalyst for acylation of alcohols with acid anhydrides or the esterification of alcohols by carboxylic acids in the presence of p-nitrobenzoic anhydrides. The remarkably high catalytic activity of scandium triflate can be used for assisting the acylation by acid anhydrides of not only primary alcohols but also sterically-hindered secondary or tertiary alcohols. The method presented is especially effective for selective macrolactonization of ω-hydroxy carboxylic acids.
A Novel Transesterification of Thioesters with Alcohols by an Electrochemical Activation
Yamaguchi, Masahiko,Tsukamoto, Yukiharu,Minami, Toru
, p. 1223 - 1226 (2007/10/02)
Esters were synthesized from thioesters and alcohols in high yields by an electrochemical activation.Different results were obtained by the use of n-Bu4N+ I- and LiBF4 as the electrolyte.
