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122375-70-6

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122375-70-6 Usage

General Description

3-AMINO-5-PHENYLTHIOPHENE-2-CARBOXAMIDE is a chemical compound with the molecular formula C11H10N2OS. It is a derivative of thienothiophene, which is a heterocyclic compound containing both sulfur and nitrogen atoms in its ring structure. 3-AMINO-5-PHENYLTHIOPHENE-2-CARBOXAMIDE is commonly used in organic synthesis and medicinal chemistry to create various pharmaceuticals and agrochemicals. It has also been studied for its potential use in the development of new materials with electronic and optoelectronic properties. Additionally, it may have applications in the field of organic electronics and as a building block for organic semiconductors. Overall, 3-AMINO-5-PHENYLTHIOPHENE-2-CARBOXAMIDE is a versatile chemical with potential uses across various scientific and industrial fields.

Check Digit Verification of cas no

The CAS Registry Mumber 122375-70-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,3,7 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 122375-70:
(8*1)+(7*2)+(6*2)+(5*3)+(4*7)+(3*5)+(2*7)+(1*0)=106
106 % 10 = 6
So 122375-70-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H10N2OS/c12-8-6-9(15-10(8)11(13)14)7-4-2-1-3-5-7/h1-6H,12H2,(H2,13,14)

122375-70-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-AMINO-5-PHENYLTHIOPHENE-2-CARBOXAMIDE

1.2 Other means of identification

Product number -
Other names 2-Thiophenecarboxamide,3-amino-5-phenyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:122375-70-6 SDS

122375-70-6Relevant articles and documents

ANTI-CANCER DRUGS AND USES RELATING THERETO FOR METASTATIC MALIGNANT MELANOMA AND OTHER CANCERS

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Page/Page column 46, (2010/04/06)

The present invention discloses triazene analogs of the general formula (I) and formula (II), their tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts thereof for the metastatic malignant melanoma and other cancers including but not limited to lymphomas, sarcomas, carcinomas, and gliomas. The invention further discloses a process for the preparation of the above said triazene analogs of formula (I) and formula (II), and their pharmaceutically acceptable compositions.

Evolution of the thienopyridine class of inhibitors of IκB kinase-β: Part I: Hit-to-lead strategies

Morwick, Tina,Berry, Angela,Brickwood, Janice,Cardozo, Mario,Catron, Katrina,DeTuri, Molly,Emeigh, Jonathan,Homon, Carol,Hrapchak, Matt,Jacober, Stephen,Jakes, Scott,Kaplita, Paul,Kelly, Terence A.,Ksiazek, John,Liuzzi, Michel,Magolda, Ronald,Mao, Can,Marshall, Daniel,McNeil, Daniel,Prokopowicz II, Anthony,Sarko, Christopher,Scouten, Erika,Sledziona, Cynthia,Sun, Sanxing,Watrous, Jane,Wu, Jiang Ping,Cywin, Charles L.

, p. 2898 - 2908 (2007/10/03)

High-throughput screening is routinely employed as a method for the identification of novel hit structures. Large numbers of active compounds are typically procured in this way and must undergo a rigorous validation process. This process is described in detail for a collection of screening hits identified as inhibitors of IκB kinase-β (IKKβ), a key regulatory enzyme in the nuclear factor-κB (NF-κB) pathway. From these studies, a promising hit series was selected. Subsequent lead generation activities included the development of a pharmacophore hypothesis and structure-activity relationship (SAR) for the hit series. This led to the exploration of related scaffolds offering additional opportunities, and the various structural classes were comparatively evaluated for enzyme inhibition, selectivity, and drug-like properties. A novel lead series of thienopyridines was thereby established, and this series advanced into lead optimization for further development.

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