1235-28-5 Usage
Benzimidazole ring
A heterocyclic aromatic ring system consisting of a benzene ring fused to a five-membered ring containing two nitrogen atoms.
Diphenylmethanol group
A functional group consisting of a benzyl alcohol (a hydroxyl group attached to a benzene ring) with two phenyl groups attached to the carbon atom bearing the hydroxyl group.
White solid
A description of the physical appearance of the compound, indicating that it is a solid at room temperature and is white in color.
Molecular weight
308.36 g/mol, indicating the mass of one mole of the compound.
Potential applications in the pharmaceutical industry
The compound's structural features make it a versatile building block for the synthesis of various biologically active compounds.
Pharmacological properties
The compound has the potential to exhibit antimicrobial, antifungal, and antiviral activities.
Interesting target for further research and development
The unique structure and properties of the compound make it a promising candidate for further study in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1235-28-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,3 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1235-28:
(6*1)+(5*2)+(4*3)+(3*5)+(2*2)+(1*8)=55
55 % 10 = 5
So 1235-28-5 is a valid CAS Registry Number.
1235-28-5Relevant articles and documents
METALLATION OF 1-DIALKYLAMINOBENZIMIDAZOLES
Kuz'menko, V. V.,Filatova, I. A.,Pozharskii, A. F.
, p. 1009 - 1014 (2007/10/02)
In contrast to 1-amino- and 1-alkylaminobenzimidazoles, 1-di-alkylaminobenzimidazoles are metallated by n-butyl-lithium in absolute ether at the 2-position.The subsequent treatment of the lithium derivatives by electrophilic reagents, in which role benzop
Synthesis of 2-Substituted Imidazoles and Benzimidazoles and of 3-Substituted Pyrazoles by Lithiation of N-(Dialkylamino)methyl Heterocycles
Katritzky, Alan R.,Rewcastle, Gordon W.,Fan, Wei-Qiang
, p. 5685 - 5689 (2007/10/02)
The lithiation of N-(dialkylamino)methyl (aminal) derivatives of imidazole, benzimidazole, and pyrazole (themselves readily available from parent heterocycles, formaldehyde, and a secondary amine) occurs smoothly at 2-, 2-, and 5-positions, respectively, upon treatment with n-butyllithium in ether or tetrahydrofuran.Reaction with electrophiles, and subsequent facile acid-catalyzed hydrolysis of the protecting group, provides 2-substituted imidazoles, 2-substituted benzimidazoles, and 3(5)-substituted pyrazoles in good overall yields.
