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1235-97-8

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1235-97-8 Usage

General Description

17-ethyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one is a synthetic steroid hormone that belongs to the class of anabolic steroids. It is a derivative of testosterone and is known for its strong anabolic properties, which promote muscle growth and development. This chemical is often used in the medical community to treat conditions such as muscle wasting and hormonal imbalances. Additionally, it is commonly abused as a performance-enhancing drug in sports due to its ability to increase muscle mass and strength. However, it is also associated with a range of negative side effects and health risks when used inappropriately, including cardiovascular issues, liver damage, and hormonal imbalances.

Check Digit Verification of cas no

The CAS Registry Mumber 1235-97-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,3 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1235-97:
(6*1)+(5*2)+(4*3)+(3*5)+(2*9)+(1*7)=68
68 % 10 = 8
So 1235-97-8 is a valid CAS Registry Number.

1235-97-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 17α-ethylandrost-4-en-17β-ol-3-one

1.2 Other means of identification

Product number -
Other names 17-Hydroxy-17βH-pregn-4-en-3-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1235-97-8 SDS

1235-97-8Downstream Products

1235-97-8Relevant articles and documents

Microbial transformation of 17α-ethynyl- and 17α-ethylsteroids, and tyrosinase inhibitory activity of transformed products

Choudhary, M. Iqbal,Sultan, Sadia,Khan, Mahmud Tareq Hassan,Rahman, Atta-ur

, p. 798 - 802 (2005)

The microbial transformation of the 17α-ethynyl-17β- hydroxyandrost-4-en-3-one (1) (ethisterone) and 17α-ethyl-17β- hydroxyandrost-4-en-3-one (2) by the fungi Cephalosporium aphidicola and Cunninghamella elegans were investigated. Incubation of compound 1 with C. aphidicola afforded oxidized derivative, 17α-ethynyl-17β- hydroxyandrosta-1,4-dien-3-one (3), while with C. elegans afforded a new hydroxy derivative, 17α-ethynyl-11α,17β-dihydroxyandrost-4-en-3-one (4). On the other hand, the incubation of compound 2 with the fungus C. aphidicola afforded 17α-ethyl-17β-hydroxyandrosta-1,4-dien-3-one (5). Two new hydroxylated derivatives, 17α-ethyl-11α,17β- dihydroxyandrost-4-en-3-one (6) and 17α-ethyl-6α,17β-dihydroxy- 5α-androstan-3-one (7) were obtained from the incubation of compound 2 with C. elegans. Compounds 1-6 exhibited tyrosinase inhibitory activity, with compound 6 being the most potent member (IC50 = 1.72 μM).

STEROID SPIROLACTONIZATION

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Page 138, (2008/06/13)

A steroid comprising a 17-spirolactone or corresponding open lactone structure is obtained by carbonylation of a 17-alkenyl or 17-alkynyl substrate. A 17-alkenyl intermediate may be prepared by semi-hydrogenation of a 17-alkynyl group. Multiple reaction schemes are disclosed for preparation of a 3-keto-9,11-epoxy-17-spirolactone steroid such as eplerenone. Novel intermediates are also disclosed, as well as steps for forming such novel intermediates, or converting them to further intermediates or products, by semi-hydrogenation, carbonylation, 6,7-dehydrogenation, furylation or other transformations or combinations thereof.

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