1236-72-2 Usage
General Description
1,3,5(10)-estratrien-2,3,16alpha,17beta-tetrol 2-methyl ether is a synthetic chemical compound that belongs to the family of estrogen hormones. It is structurally similar to the natural hormone estradiol and has been used in research studies as a tool to investigate the biological effects of estrogen on various physiological processes. 1,3,5(10)-ESTRATRIEN-2,3,16ALPHA,17BETA-TETROL 2-METHYL ETHER is also known for its potential pharmacological properties, including its ability to bind to estrogen receptors and potentially modulate hormone-dependent pathways. Additionally, the chemical has been studied for its potential use in hormone replacement therapy and as a potential treatment for conditions related to hormonal imbalances. However, further research is necessary to fully understand the effects and potential therapeutic applications of 1,3,5(10)-estratrien-2,3,16alpha,17beta-tetrol 2-methyl ether.
Check Digit Verification of cas no
The CAS Registry Mumber 1236-72-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,3 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1236-72:
(6*1)+(5*2)+(4*3)+(3*6)+(2*7)+(1*2)=62
62 % 10 = 2
So 1236-72-2 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O4/c1-19-6-5-11-12(14(19)9-16(21)18(19)22)4-3-10-7-15(20)17(23-2)8-13(10)11/h7-8,11-12,14,16,18,20-22H,3-6,9H2,1-2H3/t11-,12+,14-,16+,18-,19-/m0/s1
1236-72-2Relevant articles and documents
Isolation of 16 -hydroxy-2-methoxyestrone from rat bile.
Watanabe,Menzies
, p. 123 - 132 (1973)
-
Synthesis of 2-Methoxy- and 4-Methoxy-Estrogens with Halogen-Methoxy Exchange Reaction
Numazawa, Mitsuteri,Ogura, Yuko,Kimura, Katsuhiko,Nagaoka, Masao
, p. 3701 - 3715 (2007/10/02)
Synthesis of 2-methoxy- and 4-methoxy-estrone (6) and (9), 2-methoxy- and 4-methoxy-estradiol (15) and (18), and 2-methoxy- and 4-methoxy-estratriol (24) and (27) are described.Catalytic hydrogenation over Pd/C of 2,4-dibromo or 2,4-diiodo estrogens gave regioselectively the corresponding 4-halogeno derivatives in excellent yields.Reaction of 2-iodo or 4-iodo estradiol and 2-iodo or 4-iodo estriol with NaOCH3 in MeOH and dimethylformamide (DMF) in the presence of CuCl2 gave in an excellent yield and in a good yield, while (6) and (9) were also similarly obtained by the reaction with pyridine instead of DMF.
Syntheses of 16β oxygenated catechol estrogen methyl ethers, new and potential metabolites
Nambara,Kawarada
, p. 1613 - 1616 (2007/10/14)
-
