123760-07-6

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• Basic information

  1. Product Name: Zinostatinstimalamer
  2. Synonyms: Zinostatinstimalamer
  3. CAS NO:123760-07-6
  4. Molecular Formula:
  5. Molecular Weight:
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 123760-07-6.mol
  9. Article Data: 0

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: Zinostatinstimalamer(CAS DataBase Reference)
  10. NIST Chemistry Reference: Zinostatinstimalamer(123760-07-6)
  11. EPA Substance Registry System: Zinostatinstimalamer(123760-07-6)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 123760-07-6(Hazardous Substances Data)

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• Zinostatin stimalamer

  Cas No: 123760-07-6

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• Henan Tianfu Chemical Co., Ltd.
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123760-07-6 Usage

Description

Zinostatin stimalamer is a new antineoplastic polymeric agent launched in Japan for the treatment of hepatoma. It was synthesized by chemical conjugation of the synthetic inert poty(styrene-maleic acid) (SMA) and neocarzinostatin (NCS), which is a proteinaceous antitumor agent produced by Streptomyces carzinostaticus. SMANCS not only retains the properties of NCS for inhibiting DNA synthesis in the cell by direct DNA strand scission, but also is able to uniquely augment the host defense system by inducing interferon γ and activating macrophages. Compared with NCS, SMANCS has greatly improved in vitro and in vivo stability, is more effective in reducing tumor size and in preventing the development of new tumors, has decreased toxic side effects and extended plasma half life. In clinical trials, tumor size reductions have been obtained in 90% of patients with hepatoma and dose of 0.7 mg/m2 induced complete or almost complete necrosis of tumor without affecting noncancerous liver tissue or the gallbladder.

Brand name

SMANCS

Check Digit Verification of cas no

The CAS Registry Mumber 123760-07-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,7,6 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 123760-07:
(8*1)+(7*2)+(6*3)+(5*7)+(4*6)+(3*0)+(2*0)+(1*7)=106
106 % 10 = 6
So 123760-07-6 is a valid CAS Registry Number.

123760-07-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name	Zinostatin stimalamer

1.2 Other means of identification

Product number	-
Other names	SMANCS

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123760-07-6 SDS

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