124937-62-8 Usage
Uses
2-Methoxy-5-methyl-β-phenylbenzenepropanoic Acid Methyl Ester is a related compound to Tolterodine (T535795), a muscarinic receptor antagonist. Used in the treatment of urinary incontinence.
Check Digit Verification of cas no
The CAS Registry Mumber 124937-62-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,9,3 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 124937-62:
(8*1)+(7*2)+(6*4)+(5*9)+(4*3)+(3*7)+(2*6)+(1*2)=138
138 % 10 = 8
So 124937-62-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H20O3/c1-13-9-10-17(20-2)16(11-13)15(12-18(19)21-3)14-7-5-4-6-8-14/h4-11,15H,12H2,1-3H3
124937-62-8Relevant articles and documents
Rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to coumarins: Asymmetric synthesis of (R)-tolterodine
Chen, Gang,Tokunaga, Norihito,Hayashi, Tamio
, p. 2285 - 2288 (2007/10/03)
(Chemical Equation Presented) Rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to coumarins proceeded with high enantioselectivity in the presence of a rhodium catalyst (3 mol %) generated from Rh(acac)(C 2H4)2 and (R)-Segphos to give the corresponding (R)-4-arylchroman-2-ones in over 99% ee. This asymmetric reaction was applied to the synthesis of (R)-tolterodine.
