125412-04-6 Usage
General Description
D-Alanine, N-(2-hydroxyethyl)- (9CI) is a chemical compound consisting of D-alanine, a naturally occurring amino acid, and 2-hydroxyethyl group. It is commonly used as a building block in the synthesis of peptides. D-alanine is an important component of the peptidoglycan layer in bacterial cell walls, playing a crucial role in maintaining cell structure and integrity. Additionally, the incorporation of the hydroxyethyl group adds a hydrophilic character to the molecule, making it suitable for use as a hydrophilic linker in the synthesis of various pharmaceutical compounds. D-Alanine, N-(2-hydroxyethyl)- (9CI) may have potential applications in the development of antimicrobial agents and drug delivery systems due to its unique chemical structure and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 125412-04-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,4,1 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 125412-04:
(8*1)+(7*2)+(6*5)+(5*4)+(4*1)+(3*2)+(2*0)+(1*4)=86
86 % 10 = 6
So 125412-04-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H11NO3/c1-4(5(8)9)6-2-3-7/h4,6-7H,2-3H2,1H3,(H,8,9)/t4-/m1/s1
125412-04-6Relevant articles and documents
N-phosphorylated amino acids as potential cytostatics
Schwieger,Unterhalt
, p. 709 - 715 (2007/10/02)
Phosphoramidic dichlorides 3 are synthesized by nucleophilic attack of methyl 2-(1-ethylenimino)-alkanoates 1 on POCl3 or by the reaction of amino acid methyl ester hydrochlorides 2 with POCl3. Subsequent treatment of 3 with ethylenimine affords the TEPA-analogs 4, and with 3-(1-ethylenimino)-1-propanol (6) the IFOSFAMID analogous 1,3,2-oxaza-phosphorines 5, the cytostatic activity of which was tested in the P388-leukemia of the CD2F1-mouse.
