125983-34-8 Usage
General Description
2-(Chloromethyl)-1H-perimidine hydrochloride, also known as chlormethine hydrochloride, is a chemical compound used in the treatment of certain types of cancer, such as Hodgkin's disease and non-Hodgkin's lymphoma. It belongs to the class of nitrogen mustard alkylating agents, which work by interfering with the DNA of cancer cells, causing them to die. 2-(CHLOROMETHYL)-1H-PERIMIDINE HYDROCHLORIDE is often administered through intravenous infusion and is used in combination with other chemotherapy drugs. It is important to handle and administer 2-(Chloromethyl)-1H-perimidine hydrochloride with caution, as it can cause severe skin and eye irritation, and can be extremely harmful if ingested or inhaled. Additionally, it may have adverse effects on reproductive health and fetal development, so precautions must be taken by healthcare professionals and patients during its use.
Check Digit Verification of cas no
The CAS Registry Mumber 125983-34-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,9,8 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 125983-34:
(8*1)+(7*2)+(6*5)+(5*9)+(4*8)+(3*3)+(2*3)+(1*4)=148
148 % 10 = 8
So 125983-34-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H9ClN2/c13-7-11-14-9-5-1-3-8-4-2-6-10(15-11)12(8)9/h1-6H,7H2,(H,14,15)
125983-34-8Relevant articles and documents
Synthesis of some benzotriazole-substituted perimidines
Mobinikhaledi,Foroughifar,Goli
, p. 2549 - 2554 (2005)
2-substituted perimidines 3(a-g) were prepared from an acid-catalyzed reaction of 1,8-diaminonaphthalene with carboxylic acids using microwave irradiation. Addition of these perimidines to 1-chloromethyl benzotriazole in the presence of the sodium amide under reflux conditions gave benzotriazole-substituted perimidines 5(a-f). Yields of these products following recrystallization from water were of the order of 60-65%. IR and 1HNMR spectra and elemental analysis were used for identification of these compounds. Copyright Taylor & Francis Inc.
