126496-79-5Relevant articles and documents
A practical method for the aziridination of α,β-unsaturated carbonyl compounds with a simple carbamate utilizing sodium hypochlorite pentahydrate
Minakata, Satoshi,Umeda, Takehiro
, p. 22120 - 22124 (2021/07/02)
The efficient formation oftert-butylN-chloro-N-sodio-carbamate by the reaction of simpletert-butyl carbamate with sodium hypochlorite pentahydrate (NaOCl·5H2O) would be a practical and green method for the aziridination of α,β-unsaturated carbo
Selective cleavage of carbamate protecting groups from aziridines with otera's catalyst
Sun, Shan,Tirotta, Ilaria,Zia, Nicholas,Hutton, Craig A.
, p. 411 - 415 (2014/04/03)
Otera's distannoxane catalyst was found to promote the cleavage of carbamate groups from N-protected aziridines. This method enables the chemoselective cleavage of an aziridinyl N-carbobenzyloxy (Cbz) group in the presence of other N-Cbz groups. The selec
Use of (S)-N-tert-butoxycarbonylaziridine-2-carboxylate derivatives for α-amino acid synthesis
Baldwin, Jack E.,Farthing, Christopher N.,Russell, Andrew T.,Schofield, Christopher J.,Spivey, Alan C.
, p. 3761 - 3764 (2007/10/03)
(S)-tert-Butyl-N-tert-butoxycarbonylaziridine-2-carboxylate and (S)-tert-butyl-N-tert-butoxycarbonylaziridine-2-carboxamide were synthesised and found to react with copper 'catalysed' Grignard reagents to give protected α-amino acids in moderate to good yields.