126501-70-0 Usage
General Description
1-(2,2,2-TRIFLUOROACETYL)-4-PIPERIDINECARBOXYLIC ACID, also known as TFA-4-piperidinecarboxylic acid, is a chemical compound with the molecular formula C11H14F3NO3. It is a derivative of piperidine, a heterocyclic amine, and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The presence of the trifluoroacetyl group makes this compound valuable in organic synthesis due to its stability and ability to selectively react with other chemical groups. TFA-4-piperidinecarboxylic acid has a variety of potential applications in the pharmaceutical industry, particularly in the development of new drugs and therapeutic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 126501-70-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,5,0 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 126501-70:
(8*1)+(7*2)+(6*6)+(5*5)+(4*0)+(3*1)+(2*7)+(1*0)=100
100 % 10 = 0
So 126501-70-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H10F3NO3/c9-8(10,11)7(15)12-3-1-5(2-4-12)6(13)14/h5H,1-4H2,(H,13,14)
126501-70-0Relevant articles and documents
Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a model for this receptor site
Hibert,Hoffmann,Miller,Carr
, p. 1594 - 1600 (1990)
A conformation-activity relationship study of 5-HT3 receptor antagonists was used to define a pharmacophore and receptor map to qualitatively account for their activity. The design and synthesis of specific keto-amino-indole derivatives that are potent 5-HT3 receptor antagonists gave some support to the model.
CHEMOKING RECEPTOR ANTAGONISTS
-
Page/Page column 109, (2013/03/26)
Disclosed herein are chemokine receptor antagonists of formula (I) wherein G1, X1, X2, and X3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
Xanthamide fluorescent dyes
Gao, Jianxin,Wang, Poguang,Giese, Roger W.
, p. 6397 - 6401 (2007/10/03)
Two derivatives of fluorescein, termed "xanthamides," were prepared from fluorescein, an inexpensive dye. Relative to fluorescein, which contains a 6-phenolic OH and a 2′-carboxyl, the first derivative (5) contains a carboxymethyl ether at the 6-position
