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126643-38-7

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  • 9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylicacid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-16-propoxy-, methylester, (9S,10R,12R)-

    Cas No: 126643-38-7

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126643-38-7 Usage

Description

KT5926 is a potent and selective inhibitor of the oncogenic kinase PAK4, which is implicated in various types of cancer. It has demonstrated promising anti-cancer activity in preclinical studies, especially in breast and ovarian cancer models. With high specificity and minimal off-target effects, KT5926 is a potential candidate for targeted cancer therapy. Its mechanism of action involves the inhibition of PAK4-mediated signaling pathways, leading to the suppression of tumor cell proliferation and survival. Overall, KT5926 represents a novel and promising therapeutic agent for the treatment of PAK4-driven cancers.

Uses

Used in Oncology:
KT5926 is used as an anti-cancer agent for its ability to inhibit the PAK4 kinase, which is involved in the development and progression of various cancers. Its high specificity and minimal off-target effects make it a promising candidate for targeted cancer therapy.
Used in Cancer Research:
KT5926 is used as a research tool in cancer biology to study the role of PAK4 in cancer progression and to identify potential therapeutic targets for PAK4-driven cancers.
Used in Drug Development:
KT5926 is used in the development of new cancer therapies, as its mechanism of action targets a specific oncogenic kinase, potentially leading to more effective and less toxic treatments for patients with PAK4-driven cancers.
Used in Pharmaceutical Industry:
KT5926 is used as a potential drug candidate for the treatment of cancers where PAK4 plays a significant role in tumor growth and survival, offering a novel approach to targeted cancer therapy.

Check Digit Verification of cas no

The CAS Registry Mumber 126643-38-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,6,4 and 3 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 126643-38:
(8*1)+(7*2)+(6*6)+(5*6)+(4*4)+(3*3)+(2*3)+(1*8)=127
127 % 10 = 7
So 126643-38-7 is a valid CAS Registry Number.
InChI:InChI=1/C30H27N3O6/c1-4-11-37-15-9-10-20-17(12-15)24-25-18(14-31-28(25)34)23-16-7-5-6-8-21(16)33-27(23)26(24)32(20)22-13-19(29(35)39-36-3)30(33,2)38-22/h5-10,12,19,22H,4,11,13-14H2,1-3H3,(H,31,34)/t19-,22+,30-/m0/s1

126643-38-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name KT 5926

1.2 Other means of identification

Product number -
Other names Methyl (15S,16R,18R)-15-methyl-3-oxo-23-propoxy-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1<sup>15,18</sup>.0<sup>2,6</sup>.0<sup>7,27</sup>.0<sup>8,13</sup>.0<sup>19,26</sup>.0<sup>20,25</sup>]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboperoxoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:126643-38-7 SDS

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