126824-24-6 Usage
Description
BAPTA, TETRASODIUM SALT, also known as 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid, tetrasodium salt, is a selective calcium chelator with a 105-fold greater affinity for Ca2+ than for Mg2+. It is a high-quality and sensitive compound used in various research fields, including calcium signaling studies, signal transduction, apoptotic cascades, and neuroscience research. BAPTA, TETRASODIUM SALT is a beige powder that exhibits a UV spectrum shift from 254 to 279 nm at pH >6.0 after complexing with Ca2+.
Uses
Used in Calcium Signaling Studies:
BAPTA, TETRASODIUM SALT is used as a Ca2+-indicator for fluorescence suppression by Ca2+. It is particularly useful for spectrophotometric monitoring of extracellular Ca2+ levels, especially transient phenomena, due to its insensitivity to pH.
Used in Signal Transduction and Apoptotic Cascades:
BAPTA, TETRASODIUM SALT is employed as a selective calcium chelator with a 105-fold greater affinity for Ca2+ than for Mg2+, making it an essential tool for investigating signal transduction and apoptotic cascades.
Used in Neuroscience Research:
BAPTA, TETRASODIUM SALT is used as a neuroprotective agent in vitro against excitotoxic damage and spontaneous recurrent seizures, such as epilepsy.
Used in Cell Biology:
BAPTA, TETRASODIUM SALT is used for the measurement and control of Ca2+ levels in various cell types, including eggs, chromaffin cells, muscle cells, retinal cells, and pancreatic cells.
Used in Analytical Chemistry:
In conjunction with certain formazan dyes, BAPTA can be used in a colorimetric assay for Mg2+, making it a valuable tool in analytical chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 126824-24-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,8,2 and 4 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 126824-24:
(8*1)+(7*2)+(6*6)+(5*8)+(4*2)+(3*4)+(2*2)+(1*4)=126
126 % 10 = 6
So 126824-24-6 is a valid CAS Registry Number.