129018-59-3 Usage
Description
1-Methyl-2-nitro-6-phenylimidazo[4,5-B]pyridine is a synthetic chemical compound characterized by its bright yellow powder form. It is known for its potent mutagenic activity, making it a significant compound in the field of genetic research and mutagenesis studies.
Uses
Used in Genetic Research:
1-Methyl-2-nitro-6-phenylimidazo[4,5-B]pyridine is used as a mutagenic agent for inducing genetic mutations in various organisms, particularly in the reversion assay of Salmonella typhimurium. Its mutagenic properties allow researchers to study the mechanisms of DNA damage, repair, and genetic mutations, which are crucial for understanding the fundamentals of genetics and the development of new therapeutic strategies.
Used in Mutagenesis Research:
In the field of mutagenesis research, 1-Methyl-2-nitro-6-phenylimidazo[4,5-B]pyridine serves as a valuable tool for investigating the effects of mutations on cellular processes and the potential for developing novel genetic modifications. Its use in this context aids in the discovery of new genetic markers and the development of targeted therapies for various diseases.
Chemical Properties:
1-Methyl-2-nitro-6-phenylimidazo[4,5-B]pyridine is a bright yellow powder, which is a characteristic feature of this chemical compound. This property may be useful in identifying and distinguishing it from other compounds in laboratory settings.
Check Digit Verification of cas no
The CAS Registry Mumber 129018-59-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,0,1 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 129018-59:
(8*1)+(7*2)+(6*9)+(5*0)+(4*1)+(3*8)+(2*5)+(1*9)=123
123 % 10 = 3
So 129018-59-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H10N4O2/c1-16-11-7-10(9-5-3-2-4-6-9)8-14-12(11)15-13(16)17(18)19/h2-8H,1H3
129018-59-3Relevant articles and documents
Mapping serum albumin adducts of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine by data-dependent tandem mass spectrometry
Peng, Lijuan,Dasari, Surendra,Tabb, David L.,Turesky, Robert J.
, p. 2179 - 2193 (2013/01/15)
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a heterocyclic aromatic amine that is formed during the cooking of meats. PhIP is a potential human carcinogen: it undergoes metabolic activation to form electrophilic metabolites that bind to DNA
