129488-09-1 Usage
General Description
N-(1)-BOC-5-NITRO-INDAZOLE is a chemical compound that contains a BOC (tert-butoxycarbonyl) protecting group and a nitro group attached to an indazole ring. The BOC group is often used in organic synthesis to protect amines, while the nitro group is known for its electron-withdrawing properties. Indazoles are heterocyclic aromatic compounds that have been used in the development of pharmaceuticals and agrochemicals. The presence of the BOC and nitro groups in N-(1)-BOC-5-NITRO-INDAZOLE makes it a valuable intermediate for the synthesis of a variety of indazole-based compounds with potential applications in medicinal and agricultural chemistry. Its unique structural properties and reactivity make it a valuable building block for the preparation of diverse chemical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 129488-09-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,4,8 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 129488-09:
(8*1)+(7*2)+(6*9)+(5*4)+(4*8)+(3*8)+(2*0)+(1*9)=161
161 % 10 = 1
So 129488-09-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N3O4/c1-12(2,3)19-11(16)14-10-5-4-9(15(17)18)6-8(10)7-13-14/h4-7H,1-3H3
129488-09-1Relevant articles and documents
Synthesis of novel N-Aryl-1H-indazolamines from amino-1H-indazoles and arylboronic acids
Swamy, Udutha Kumara,Mohan, H. Rama,Prasad, U. Viplava
, p. 7539 - 7543 (2014)
An efficient and high-yielding synthesis of N-aryl-1H-indazolamines from amino-1H-indazole and arylboronic acids are described. In this study a series of novel N-aryl-1H-indazolamines (1a-i) were synthesized using arylboronic acids and amino-1 H-indazoles
RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AS WELL AS PREPARATION METHOD AND USE THEREOF
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Paragraph 0104; 0105, (2019/01/11)
The present invention relates to a Rho-associated protein kinase inhibitor of Formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and use thereof for the prevention or treatment of a disease mediated by the Rho-associated protein kinase (ROCK).
HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES
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Paragraph 000370, (2016/05/02)
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions in need of inhibition of heparan sulfate biosynthesis.
