130045-74-8

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Basic information

Product Name: 1-Piperazineethanol, 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-alpha-(2 ,3-dihydro-2-methyl-1,4-benzodioxin-2-yl)-, hydrochloride
Synonyms: 1-Piperazineethanol, 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-alpha-(2 ,3-dihydro-2-methyl-1,4-benzodioxin-2-yl)-, hydrochloride
CAS NO:130045-74-8
Molecular Formula: C25H31 N5 O5 . x Cl H
Molecular Weight: 0
EINECS: N/A
Product Categories: N/A
Mol File: 130045-74-8.mol
Article Data: 0

Chemical Properties

Melting Point: N/A
Boiling Point: 695°Cat760mmHg
Flash Point: 374.2°C
Appearance: /
Density: g/cm³
Vapor Pressure: 2.8E-20mmHg at 25°C
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-Piperazineethanol, 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-alpha-(2 ,3-dihydro-2-methyl-1,4-benzodioxin-2-yl)-, hydrochloride(CAS DataBase Reference)
NIST Chemistry Reference: 1-Piperazineethanol, 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-alpha-(2 ,3-dihydro-2-methyl-1,4-benzodioxin-2-yl)-, hydrochloride(130045-74-8)
EPA Substance Registry System: 1-Piperazineethanol, 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-alpha-(2 ,3-dihydro-2-methyl-1,4-benzodioxin-2-yl)-, hydrochloride(130045-74-8)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 130045-74-8(Hazardous Substances Data)

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130045-74-8 Usage

Use

Medication for the treatment of non-small cell lung cancer and pancreatic cancer

Mechanism

Inhibits the activity of a specific enzyme involved in the growth and spread of cancer cells

Form

Tablet (taken orally)

Prescription

Often part of a comprehensive treatment plan for cancer patients

Supervision

Should be used only under the supervision of a qualified healthcare professional due to potential for serious side effects and interactions with other medications.

Check Digit Verification of cas no

The CAS Registry Mumber 130045-74-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,0,4 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 130045-74:
(8*1)+(7*3)+(6*0)+(5*0)+(4*4)+(3*5)+(2*7)+(1*4)=78
78 % 10 = 8
So 130045-74-8 is a valid CAS Registry Number.

InChI:InChI=1/C25H31N5O5.ClH/c1-25(15-34-18-6-4-5-7-19(18)35-25)22(31)14-29-8-10-30(11-9-29)24-27-17-13-21(33-3)20(32-2)12-16(17)23(26)28-24;/h4-7,12-13,22,31H,8-11,14-15H2,1-3H3,(H2,26,27,28);1H

130045-74-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-1-(3-methyl-2H-1,4-benzodioxin-3-yl)ethanol,hydrochloride

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130045-74-8 SDS

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