13134-31-1 Usage
Description
2,3-Pyrazinediamine, also known as Amidol, is a chemical compound with the formula C4H6N4. It is a derivative of pyrazine, which belongs to a class of organic compounds known as diamines. Diamines are organic compounds containing two amine groups. 2,3-Pyrazinediamine is an important chemical reagent often used in the synthesis of other complex organic compounds. It is a white crystalline solid that is soluble in water and has a slightly pungent smell. It is advised to handle this chemical with care as it is a potential eye irritant and may be harmful if inhaled or swallowed.
Uses
Used in Chemical Synthesis:
2,3-Pyrazinediamine is used as a chemical reagent for the synthesis of other complex organic compounds. Its presence in the molecular structure allows for the formation of various derivatives, making it a versatile building block in organic chemistry.
Used in Pharmaceutical Industry:
2,3-Pyrazinediamine is used as an intermediate in the production of certain pharmaceuticals. Its ability to form stable bonds with other molecules makes it a valuable component in the development of new drugs and medications.
Used in Research and Development:
2,3-Pyrazinediamine is used as a research compound in academic and industrial laboratories. Its unique properties and reactivity make it an interesting subject for studies in organic chemistry, material science, and related fields.
Used in Dye and Pigment Industry:
2,3-Pyrazinediamine is used as a precursor in the production of dyes and pigments. Its chemical structure can be modified to create a range of colors, making it a valuable component in the formulation of various colorants.
Check Digit Verification of cas no
The CAS Registry Mumber 13134-31-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,3 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13134-31:
(7*1)+(6*3)+(5*1)+(4*3)+(3*4)+(2*3)+(1*1)=61
61 % 10 = 1
So 13134-31-1 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N4/c5-3-4(6)8-2-1-7-3/h1-2H,(H2,5,7)(H2,6,8)
13134-31-1Relevant articles and documents
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McDonald,Ellingson
, p. 1034,1035 (1947)
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Imidazopyridine- and purine-thioacetamide derivatives: Potent inhibitors of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1)
Chang, Lei,Lee, Sang-Yong,Leonczak, Piotr,Rozenski, Jef,De Jonghe, Steven,Hanck, Theodor,Müller, Christa E.,Herdewijn, Piet
, p. 10080 - 10100 (2015/02/05)
Nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) belongs to the family of ecto-nucleotidases, which control extracellular nucleotide, nucleoside, and (di)phosphate levels. To study the (patho)physiological roles of NPP1 potent and selective inhibitors with drug-like properties are required. Therefore, a compound library was screened for NPP1 inhibitors using a colorimetric assay with p-nitrophenyl 5′-thymidine monophosphate (p-Nph-5′-TMP) as an artificial substrate. This led to the discovery of 2-(3H-imidazo[4,5-b]pyridin-2-ylthio)-N-(3,4-dimethoxyphenyl)acetamide (5a) as a hit compound with a Ki value of 217 nM. Subsequent structure-activity relationship studies led to the development of purine and imidazo[4,5-b]pyridine analogues with high inhibitory potency (Ki values of 5.00 nM and 29.6 nM, respectively) when assayed with p-Nph-5′-TMP as a substrate. Surprisingly, the compounds were significantly less potent when tested versus ATP as a substrate, with Ki values in the low micromolar range. A prototypic inhibitor was investigated for its mechanism of inhibition and found to be competitive versus both substrates.
Studies on Pyrazines. Part 33.1 Synthesis of 2,3-Diaminopyrazines via [1,2,5]Thiadiazolo[3,4-b] pyrazines
Sato, Nobuhiro,Mizuno, Hajime
, p. 250 - 251 (2007/10/03)
The syntheses of [1,2,5]thiadiazolo[3,4-b]pyrazine (3) and its methyl and/or phenyl derivatives as well as their reduction to 2,3-diaminopyrazines 4 are described.