13182-82-6 Usage
Description
Metronidazole Acetate is an imidazole derivative that serves as a protected form of Metronidazole (M338880). It exhibits anti-trichomonas, antifungal, and spermicidal properties, making it a versatile compound for various applications.
Uses
Used in Pharmaceutical Industry:
Metronidazole Acetate is used as an active pharmaceutical ingredient for the treatment of various infections caused by protozoa, such as trichomoniasis, and anaerobic bacteria. Its antifungal and spermicidal properties also contribute to its use in this industry.
Used in Veterinary Medicine:
In the veterinary field, Metronidazole Acetate is used as a broad-spectrum antiprotozoal and antibacterial agent for the treatment of infections in animals.
Used in Contraceptives:
Due to its spermicidal activity, Metronidazole Acetate can be used in the development of contraceptive products to prevent pregnancy.
Used in Antifungal Treatments:
Metronidazole Acetate's antifungal properties make it suitable for use in treatments targeting fungal infections, both in humans and animals.
Used in Research:
As a pale yellow solid with unique chemical properties, Metronidazole Acetate can be utilized in research settings to study the effects of imidazole derivatives on various biological systems and to develop new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 13182-82-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,8 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13182-82:
(7*1)+(6*3)+(5*1)+(4*8)+(3*2)+(2*8)+(1*2)=86
86 % 10 = 6
So 13182-82-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N3O4/c1-6-9-5-8(11(13)14)10(6)3-4-15-7(2)12/h5H,3-4H2,1-2H3
13182-82-6Relevant articles and documents
Imidazole derivatives as possible microbicides with dual protection
Kumar, Lalit,Sarswat, Amit,Lal, Nand,Sharma, Vishnu L.,Jain, Ashish,Kumar, Rajeev,Verma, Vikas,Maikhuri, Jagdamba P.,Kumar, Awanit,Shukla, Praveen K.,Gupta, Gopal
experimental part, p. 817 - 824 (2010/04/06)
Twenty seven derivatives (2-28) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol were synthesized and evaluated for anti-trichomonas, spermicidal and antifungal activities. Twenty six compounds were active against Trichomonas vaginalis at MIC ranging from 1-42 μM and seven compounds (9,18,19,22,24,26,28) immobilized 100% human spermatozoa at 1% concentration (w/v). Twenty three compounds (2,3,5,8-26,28) exhibited antifungal activity at 25-50 μg/mL concentration. Seven compounds (9,18,19,22,24,26,28) showed significant anti-trichomonas and spermicidal activities and also exhibited mild antifungal activity. All the compounds were highly safe towards human cervical cell line (HeLa) as shown by the cell-viability assay of HeLa cells at 200 μg/mL concentration, whereas nonoxynol-9 (N-9, the marketed spermicidal microbicide) was highly cytotoxic. Therefore, it may be concluded that introduction of the pharmacophore responsible for spermicidal activity into a proven anti-trichomonas structure may lead to a potent dual function microbicide better and safer than N-9.
Pharmaceutical compositions primarily for the treatment and prevention of genitourinary infections and their extragenital complications
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, (2008/06/13)
Compositions having synergistic effective amounts of one or more antibacterial agents, a nitroimidazole, and/or a sulfonamide or a molecule or compound having folic acid antagonist effect and nitroimidazole substitution in addition, with or without an ant