13274-42-5Relevant articles and documents
Macrocyclic Polyamines Deplete Cellular ATP Levels and Inhibit Cell Growth in Human Prostate Cancer Cells
Frydman, Benjamin,Bhattacharya, Subhra,Sarkar, Aparajita,Drandarov, Konstantin,Chesnov, Sergiy,Guggisberg, Armin,Popaj, Kasim,Sergeyev, Sergey,Yurdakul, Aysil,Hesse, Manfred,Basu, Hirak S.,Marton, Laurence J.
, p. 1051 - 1059 (2004)
In solid tumors, when 02 partial pressure drops below 10 mmHg, ATP levels rapidly decrease due to the Warburg effect. It is known that certain macrocyclic polyamines catalyze the chemical hydrolysis of ATP with release of inorganic phosphate. Since tumor
METHOD FOR PRODUCING BIS-[(3-DIMETHYLAMINO)PROPYL]AMINE (DIPROPYLENE TRIAMINE, DPTA)
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Page/Page column 2; 3; 9, (2008/06/13)
The invention relates to a method for producing bis-[(3-dimethylamino)propyl]amine (dipropylene triamine, DPTA) by continuously reacting 1,3-propylene diamine (1,3-PDA) in the presence of a heterogeneous catalyst. The inventive method is characterized by