13373-31-4 Usage
Chemical structure
A complex chemical compound with an acetamido group, an indolylmethyl group, and two ethyl groups attached to a malonate molecule.
Acetamidi group
The presence of this group suggests potential pharmaceutical applications, as it can improve solubility and bioavailability of drugs.
Indolylmethyl group
Derived from the indole molecule, which is known for its diverse biological activities, including anti-inflammatory, anti-oxidant, and anti-cancer properties.
Pharmaceutical potential
Due to the combination of functional groups, this compound may hold promise for further research in the development of new pharmaceuticals or bioactive compounds.
Biological activities
The presence of the indolylmethyl group suggests that the compound may exhibit a range of biological activities, such as anti-inflammatory, anti-oxidant, and anti-cancer properties.
Solubility
The acetamido group may contribute to the compound's solubility in water or other solvents, which is important for its potential use in pharmaceutical formulations.
Bioavailability
The acetamido group may also enhance the compound's bioavailability, allowing it to be more easily absorbed and utilized by the body.
Research opportunities
The unique structure and potential biological activities of this compound make it an interesting candidate for further research in the fields of medicinal chemistry and drug development.
Structural diversity
The combination of different functional groups in the molecule provides a basis for exploring various modifications and derivatives, which could lead to the discovery of new bioactive compounds with improved properties.
Check Digit Verification of cas no
The CAS Registry Mumber 13373-31-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,7 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13373-31:
(7*1)+(6*3)+(5*3)+(4*7)+(3*3)+(2*3)+(1*1)=84
84 % 10 = 4
So 13373-31-4 is a valid CAS Registry Number.
13373-31-4Relevant articles and documents
Synthesis of 3-Amino-5H-pyridoindoles, Carcinogenic γ-Carbolines
Akimoto, Hiroshi,Kawai, Akiyoshi,Nomura,Hiroaki
, p. 123 - 130 (2007/10/02)
The carcinogenic γ-carbolines 3-amino-1,4-dimethyl-5H-pyridoindole (1) and 3-amino-1-methyl-5H-pyridoindole (2) were synthesized efficiently by the following procedures.The key method involved the acid-catalyzed cyclization of 2-acetamido-3-(2-indolyl)alkanoic acids to 1,2-dihydro-γ-carbolines.This was followed by dehydrogenation to the γ-carbolinecarboxylates and conversion of the ester group to the carboxyl and finally to the amino one by Curtius rearrangement.Alternative methods involved the thermolysis of 4-(1-benzotriazolyl)-3,6-dimethyl-2-pyridinamine to synthesize 1 and the condensation of 3-acetylindole-2-acetonitrile with ammonia to synthesize 2.The structures of γ-carbolines 1 and 2 were unambiguously established by comparing samples of each synthesized by the two different routes.A selective and one-step synthesis of ethyl 2-acetamido-3-(2-indolyl)alkanoates was newly exploited starting from diethyl acetamidomalonate and quaternary ammonium salts of 2-indoles.