134031-24-6 Usage
Description
2,4-Dichloropyridine-3-carboxaldehyde is a chemical compound characterized by its molecular formula C6H3Cl2NO. It is a highly versatile and reactive compound, known for its unique chemical structure that makes it an essential building block in the synthesis of a variety of pharmaceuticals and agrochemicals. Its reactivity and potential applications in organic synthesis and as a reagent in chemical reactions have garnered significant interest in the scientific community. However, due to its hazardous and toxic nature to the environment, it requires careful handling and management.
Uses
Used in Pharmaceutical Industry:
2,4-Dichloropyridine-3-carboxaldehyde is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into the molecular structures of drugs, enhancing their therapeutic properties and effectiveness.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-Dichloropyridine-3-carboxaldehyde is utilized as a precursor in the production of pesticides, contributing to the development of more effective and targeted pest control solutions.
Used in Organic Synthesis:
2,4-Dichloropyridine-3-carboxaldehyde is employed as a reagent in organic synthesis, facilitating the creation of complex organic compounds and contributing to the advancement of chemical research and development.
Used as a Research Reagent:
In academic and research settings, 2,4-Dichloropyridine-3-carboxaldehyde is used as a reagent to study its properties and potential applications, furthering the understanding of its role in chemical reactions and its integration into new compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 134031-24-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,0,3 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 134031-24:
(8*1)+(7*3)+(6*4)+(5*0)+(4*3)+(3*1)+(2*2)+(1*4)=76
76 % 10 = 6
So 134031-24-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H3Cl2NO/c7-5-1-2-9-6(8)4(5)3-10/h1-3H
134031-24-6Relevant articles and documents
Reactivity and regioselectivity in Stille couplings of 3-substituted 2,4-dichloropyridines
Khoje, Abhijit Datta,Gundersen, Lise-Lotte
, p. 523 - 525 (2011)
The influence of substituents at C-3 of 2,4-dichloropyridines on their reactivity and regioselectivity in Pd-catalyzed cross-couplings is studied. As a model reaction, the (Ph3P)2PdCl2-catalyzed Stille coupling between 2-furyl(tributyl)tin and pyridines is chosen. Increased electron-withdrawing ability of a substituent at the pyridine 3-position improves the overall reactivity. Absolute selectivity for coupling at C-2 is achieved with an amino group at C-3, and the selectivity is totally reversed when the amino group is exchanged for a nitro substituent.
PROCESS FOR PREPARING BTK INHIBITORS
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Paragraph 0286-0297, (2018/07/05)
Methods for preparing the Bruton's Tyrosine Kinase ("BTK") inhibitor compound 2- {3'-hydroxymethyl-1-methyl-5-[5-((S)-2-methyl-4-oxetan-3-yl-piperazin-1-yl)-pyridin-2- ylamino]-6-oxo-1,6-dihydro-[3,4']bipyridinyl-2'-yl}-7,7-dimethyl-3,4,7,8-tetrahydro-2H,6H- cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1-one are provided. Methods for preparing tricyclic lactam compounds are also provided.
ARYL ETHER-BASE KINASE INHIBITORS
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Page/Page column 126, (2015/03/28)
The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
