13504-15-9Relevant articles and documents
Non-hormonal steroid modulators of NF-κβ for treatment of disease
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Page/Page column 42-43; 44, (2019/11/18)
The present invention relates to compounds and methods which may be useful as treatments of diseases.
NON-HORMONAL STEROID MODULATORS OF NF-KB FOR TREATMENT OF DISEASE
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Paragraph 0208, (2013/06/27)
The present invention relates to compounds and methods which may be useful as treatments of diseases.
Catalytic Epoxidation of Alkenes with Oxone
Denmark, Scott E.,Forbes, David C.,Hays, David S.,DePue, Jeffrey S.,Wilde, Richard G.
, p. 1391 - 1407 (2007/10/02)
A practical, general and efficient protocol for the catalytic epoxidation of alkenes has been developed.The in situ generation of reactive dioxiranes capable of epoxidizing a variety of alkenes under biphasic conditions has been accomplished using phase transfer catalysts bearing a carbonyl group.Optimal epoxidation conditions employ 10 mol percent of 1-dodecyl-1-methyl-4-oxopiperidinium triflate (8d(+)OTf(-)) in a CH2Cl2/pH 7.5-8.0 biphase using potassium monoperoxosulfate (Oxone) as the oxidant.Optimization of the conditions identified (1) slow addition rate, (2) pH 7.5-8.0, (3) N-dodecyl chain, and (4) the triflate salt as key experimental and structural variables.A selection of nine olefins was successfully oxidized to the corresponding epoxides in 83-96percent yield.