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135374-80-0

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135374-80-0 Usage

General Description

Maxadilan is a peptide found in the salivary glands of the sand fly, and it is responsible for the vasodilatory effects of their bite. The peptide acts by binding to receptors in the blood vessels, leading to the release of nitric oxide and other vasodilatory compounds, causing the blood vessels to relax and widen. This results in increased blood flow to the site of the bite, which may help the sand fly to feed more efficiently. Maxadilan has been studied for its potential applications in treating cardiovascular diseases, such as hypertension and ischemic heart disease, as well as for its potential use in improving blood flow in ischemic tissues.

Check Digit Verification of cas no

The CAS Registry Mumber 135374-80-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,3,7 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 135374-80:
(8*1)+(7*3)+(6*5)+(5*3)+(4*7)+(3*4)+(2*8)+(1*0)=130
130 % 10 = 0
So 135374-80-0 is a valid CAS Registry Number.

135374-80-0Upstream product

135374-80-0Downstream Products

135374-80-0Related news

The selective PAC1 receptor agonist maxadilan (cas 135374-80-0) inhibits neurogenic vasodilation and edema formation in the mouse skin08/10/2019

We have earlier shown that PACAP-38 decreases neurogenic inflammation. However, there were no data on its receptorial mechanism and the involvement of its PAC1 and VPAC1/2 receptors (PAC1R, VPAC1/2R) in this inhibitory effect.Neurogenic inflammation in the mouse ear was induced by topical applic...detailed

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