135936-36-6 Usage
General Description
"(R) (+) DICHLOROPHENYL AMINO ALCOHOL" is a chemical compound that is characterized by its molecular structure containing a dichlorophenyl group bonded to an amino alcohol moiety. It exists in two enantiomeric forms, with the (R) or (+) configuration being the specific orientation of the molecules. (R) (+) DICHLOROPHENYL AMINO ALCOHOL has various applications in the pharmaceutical and chemical industries, primarily as a building block for the synthesis of other complex compounds. It is known for its potential chiral properties, making it valuable in the production of pharmaceutical drugs, agrochemicals, and other fine chemicals. The compound's precise properties and applications may vary depending on its specific use, but its significance lies in its role as a versatile intermediate in synthetic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 135936-36-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,9,3 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 135936-36:
(8*1)+(7*3)+(6*5)+(5*9)+(4*3)+(3*6)+(2*3)+(1*6)=146
146 % 10 = 6
So 135936-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H5Cl2NO/c7-5-3-1-2-4-6(5)9(8)10/h1-4,10H
135936-36-6Relevant articles and documents
4-Amino-2-(aryl)-butylbenzamides and their conformationally constrained analogues. Potent antagonists of the human neurokinin-2 (NK2) receptor
MacKenzie, A. Roderick,Marchington, Allan P.,Middleton, Donald S.,Newman, Sandra D.,Selway, Christopher N.,Terrett, Nicholas K.
, p. 2211 - 2215 (2007/10/03)
A library, evaluating a range of piperazines, piperidines and acyclic amines, as replacements for the 4-hydroxy-4-phenylpiperidine moiety in lead (1b) was prepared. These efforts identified the 4-((N)-benzimidazolone)piperidine analogue (2a) which was further optimised using classical single-compound synthesis to yield the 3-((N)-morpholino)azetidine (2j). Conformationally constrained analogues of (2j), generally offered no potency advantage in this particular series.
PIPERIDINE DERIVATIVES, PROCESS FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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, (2008/06/13)
Piperidine derivatives, process for obtaining them and pharmaceutical compositions containing them, of formula STR1 used as neurokinin receptor antagonists, which are, in particular, useful for the treatment of all substance P-and neurokinin-dependent pathologies.
SUBSTITUTED BENZENE-FUSED HETERO AND CARBOCYCLICS AS NUEROKININ ANTAGONISTS
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, (2008/06/13)
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