136815-01-5 Usage
General Description
N-ACETYL-2-(4-FLUOROPHENYL)-L-GLYCINE is a chemical compound that belongs to the class of amino acids. It is composed of an N-acetyl group, a 4-fluorophenyl group, and a glycine moiety. N-ACETYL-2-(4-FLUOROPHENYL)-L-GLYCINE has potential applications in pharmaceutical and medical fields, particularly in the development of drugs targeting specific receptors or enzymes. It may also be used in research and development of new chemical entities. Additionally, it is important to handle and store this compound in accordance with safety guidelines, as it may pose health and environmental hazards if not handled properly.
Check Digit Verification of cas no
The CAS Registry Mumber 136815-01-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,8,1 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 136815-01:
(8*1)+(7*3)+(6*6)+(5*8)+(4*1)+(3*5)+(2*0)+(1*1)=125
125 % 10 = 5
So 136815-01-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H10FNO3/c1-6(13)12-9(10(14)15)7-2-4-8(11)5-3-7/h2-5,9H,1H3,(H,12,13)(H,14,15)/t9-/m0/s1
136815-01-5Relevant articles and documents
Chemoenzymatic approaches to the dynamic kinetic asymmetric synthesis of aromatic amino acids
Chaplin, Jennifer A.,Levin, Michael D.,Morgan, Brian,Farid, Nancy,Li, Jen,Zhu, Zuolin,McQuaid, Jeff,Nicholson, Lawrence W.,Rand, Cynthia A.,Burk, Mark J.
, p. 2793 - 2796 (2007/10/03)
Enzymatic approaches for the production of amino acids by nitrilases are described. Dynamic kinetic asymmetric synthesis conditions were established for the aromatic aminonitriles, phenylglycinonitrile and 4- fluorophenylglycinonitrile, at high pH to produce the corresponding amino acid products in high enantiomeric excess. N-Acylation of aromatic aminonitriles led to spontaneous racemization at pH 8, allowing preferential enzymatic hydrolysis of the (R)-enantiomer to afford the product N-acylamino acids in up to 99% enantiomeric excess (ee).
