13745-86-3Relevant articles and documents
Synthesis of diverse fused tetracyclic thiazepine-chalcone derivatives by claisen-schmidt condensation reaction and their antimicrobial activity
Hirani, Jayanti B.,Pandya, Mayank K.,Koradiya, Suresh B.
, p. 2860 - 2864 (2020)
To develop antimicrobial agent, a series of thiazepine-chalcones was synthesized by Claisen-Schmidt condensation between the couplings of aryl ketone in three steps protocol and different aromatic aldehydes under strong base catalyst at room temperature. The characterization of final products were carried out by IR, 1H & 13C NMR and elemental analysis. The synthesized compounds were also evaluated for their antibacterial and antifungal activities using specific Gram positive and Gram-negative bacterial strains using cup plate method.
INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF
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, (2020/08/09)
Disclosed are a compound as shown in formula (I) as an influenza virus replication inhibitor and a preparation method therefor, a pharmaceutical composition comprising the compound and the use of the compound and pharmaceutical composition thereof in the treatment of influenza.
Antibodies to quetiapine haptens and use thereof
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, (2018/01/20)
Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.