138561-22-5Relevant articles and documents
Nonsteroidal anti-inflammatory drugs as scaffolds for the design of 5- lipoxygenase inhibitors
Kolasa,Brooks,Rodriques,Summers,Dellaria,Hulkower,Bouska,Bell,Carter
, p. 819 - 824 (2007/10/03)
Representative nonsteroidal anti-inflammatory drug (NSAID) cyclooxygenase inhibitors such as ibuprofen, naproxen, and indomethacin were used as orally bioavailable scaffolds to design selective 5-lipoxygenase (5- LO) inhibitors. Replacement of the NSAID c