13961-64-3Relevant articles and documents
Biomimetic Asymmetric Reduction of Quinazolinones with Chiral and Regenerable NAD(P)H Models
Zhao, Zi-Biao,Li, Xiang,Wu, Bo,Zhou, Yong-Gui
supporting information, p. 714 - 718 (2020/05/04)
A facile approach to chiral dihydroquinazolinone derivatives has been described via biomimetic asymmetric reduction of quinazolinones with chiral and regenerable NAD(P)H models. The utility of this method was demonstrated by a concise synthesis of the bromodomain protein divalent inhibitor.
Production of quinazolinone compounds
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, (2008/06/13)
2(1H)-Quinazolinone derivatives, which are useful as anti-inflammatory agents, are prepared by heating or hydrolyzing an acylurea derivative. The acylurea derivative can be prepared by either reacting an indole derivative with an oxidizing agent or reacti