140659-87-6Relevant articles and documents
Modified oligonucleotides
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, (2008/06/13)
Novel compounds that mimic and/or modulate the activity of wild-type nucleic acids are provided. The novel compounds have modified internucleoside linkages which preferably replace naturally-occurring phosphodiester-5'-methylene linkages with four atom li
Backbone modified oligonucleotide analogs
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, (2008/06/13)
Therapeutic oligonucleotide analogs which have improved nuclease resistance and improved cellular uptake are provided. Replacement of the normal phosphorodiester inter-sugar linkages found in wild type oligomers with four atom linking groups forms unique
Oligonucleosides: Synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences
Vasseur,Debart,Sanghvi,Cook
, p. 4006 - 4007 (2007/10/02)
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