141579-54-6

• 

• Basic information

  1. Product Name: fenleuton
  2. Synonyms: fenleuton;1-(4-(3-(4-fluorophenoxy)phenyl)but-3-yn-2-yl)-1-hydroxyurea
  3. CAS NO:141579-54-6
  4. Molecular Formula: C₁₇H₁₅FN₂O₃
  5. Molecular Weight: 314.315
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 141579-54-6.mol
  9. Article Data: 3

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 489.5°Cat760mmHg
  3. Flash Point: 249.8°C
  4. Appearance: /
  5. Density: 1.36g/cm³
  6. Vapor Pressure: 2.14E-10mmHg at 25°C
  7. Refractive Index: 1.643
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. CAS DataBase Reference: fenleuton(CAS DataBase Reference)
  11. NIST Chemistry Reference: fenleuton(141579-54-6)
  12. EPA Substance Registry System: fenleuton(141579-54-6)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 141579-54-6(Hazardous Substances Data)

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• Usage
• SDS
• Upstream product
• Downstream Products
• Article

141579-54-6 Suppliers

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• N-HYDROXY-N-[4-(3-(4-FLUOROPHENOXY)PHENYL)-3-BUTYN-2-YL]UREA

  Cas No: 141579-54-6

• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

• 1-100 Metric Ton/Month

• Dayang Chem (Hangzhou) Co.,Ltd.
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• Urea,N-[3-[3-(4-fluorophenoxy)phenyl]-1-methyl-2-propyn-1-yl]-N-hydroxy-

  Cas No: 141579-54-6

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• 5

• Hangzhou J&H Chemical Co., Ltd.
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• 1-[4-[3-(4-fluorophenoxy)phenyl]but-3-yn-2-yl]-1-hydroxyurea

  Cas No: 141579-54-6

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• BOC Sciences
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• N-HYDROXY-N-[4-(3-(4-FLUOROPHENOXY)PHENYL)-3-BUTYN-2-YL]UREA

  Cas No: 141579-54-6

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• Henan Fine Chemicals Co., Ltd
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• N-Hydroxy-N-[4-(3-(4-fluorophenoxy)phenyl)-3-butyn-2-yl]urea

  Cas No: 141579-54-6

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• Shanghai Run-Biotech Co., Ltd.
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141579-54-6 Usage

Uses

Inhibitor (5-lipoxygenase, veterinary).

Brand name

LoFrin (Abbott）.

Check Digit Verification of cas no

The CAS Registry Mumber 141579-54-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,5,7 and 9 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 141579-54:
(8*1)+(7*4)+(6*1)+(5*5)+(4*7)+(3*9)+(2*5)+(1*4)=136
136 % 10 = 6
So 141579-54-6 is a valid CAS Registry Number.

InChI:InChI=1/C17H15FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-4,7-12,22H,1H3,(H2,19,21)

141579-54-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-[4-[3-(4-fluorophenoxy)phenyl]but-3-yn-2-yl]-1-hydroxyurea

1.2 Other means of identification

Product number	-
Other names	Fenleuton

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141579-54-6 SDS

141579-54-6Upstream product

• 100238-69-5 dimethylsilyl isocyanate 
• 188534-03-4 4-[3-(4-fluorophenoxy)phenyl]-3-butyn-2-ol 
• 1118-02-1 trimethylsilyl isocyanate 
• 188534-07-8 N-[4-(3-(4-fluorophenoxy)phenyl)-3-butyn-2-yl]hydroxylamine 

141579-54-6Downstream Products

141579-54-6Relevant articles and documents

Process for the preparation of arylalkynyl-N-hydroxyurea derivatives having lipoxygenase inhibitory activity

-

, (2008/06/13)

The present invention provides a process for the preparation of a compound of formula STR1 wherein R is a straight or branched alkyl group of from one to twelve carbon atoms; M represents hydrogen or a pharmaceutically acceptable cation; and A is selected from optionally substituted carbocyclic phenyl.

ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY

-

, (2008/06/13)

Compounds of the structure where p and q are zero or one, but cannot both be the same, M is a pharmaceutically acceptable cation or a metabolically cleavable group, B is a valence bond or a straight or branched alkylene group, R is alkyl, cycloalkyl or --NR1 R2, where R1 and R2 are hydrogen, alkyl, cycloalkyl or alkanoyl, and A is optionally substituted carbocyclic aryl, furyl, benzo[b]furyl, thienyl, or benzo[b]thienyl are potent inhibitors of lipoxygenase enzymes and thus inhibit the biosynthesis of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states.

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