14160-65-7Relevant articles and documents
GLUCOCORTICOID RECEPTOR MODULATORS
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Paragraph 00213, (2020/05/19)
Described herein are glucocorticoid receptor modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer and hypercortisolism.
Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2)
Yang, Michael G.,Xiao, Zili,Shi, Qing,Cherney, Robert J.,Tebben, Andrew J.,De Lucca, George V.,Santella III, Joseph B.,Mo, Ruowei,Cvijic, Mary Ellen,Zhao, Qihong,Barrish, Joel C.,Carter, Percy H.
scheme or table, p. 1384 - 1387 (2012/03/26)
We report the synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamides (4) as CCR2 inhibitors for the potential treatment of inflammatory diseases. Several of the compounds display nanomolar binding affinity for CCR2. The in vitro structure-activity
Cyclic derivatives as modulators of chemokine receptor activity
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Page/Page column 108, (2008/06/13)
The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the treatment of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.
