142763-10-8

• 

• Basic information

  1. Product Name: (R)-2-CHLORO-1-(3-CHLOROPHENYL)ETHANOL
  2. Synonyms: (R)-2-CHLORO-1-(3-CHLOROPHENYL)ETHANOL;(R)-1-(3-Chlorophenyl)-2-chloroethanol;(R)-2-Chloro-1chlorophenyl)ethanol;(R)-2-chloro-1-(4-chlorophenyl)ethanol;(R)-2-chloro-1-(3-chlorophenyl)ethano
  3. CAS NO:142763-10-8
  4. Molecular Formula: C₈H₈Cl₂O
  5. Molecular Weight: 191.05
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 142763-10-8.mol
  9. Article Data: 15

• Chemical Properties

  1. Melting Point: 110-120 °C
  2. Boiling Point: 285 ºC
  3. Flash Point: 119 ºC
  4. Appearance: /
  5. Density: 1.328
  6. Vapor Pressure: 0.00138mmHg at 25°C
  7. Refractive Index: 1.568
  8. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
  9. Solubility: N/A
  10. PKA: 12.94±0.20(Predicted)
  11. CAS DataBase Reference: (R)-2-CHLORO-1-(3-CHLOROPHENYL)ETHANOL(CAS DataBase Reference)
  12. NIST Chemistry Reference: (R)-2-CHLORO-1-(3-CHLOROPHENYL)ETHANOL(142763-10-8)
  13. EPA Substance Registry System: (R)-2-CHLORO-1-(3-CHLOROPHENYL)ETHANOL(142763-10-8)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 142763-10-8(Hazardous Substances Data)

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142763-10-8 Suppliers

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• (R)-2-CHLORO-1-(3-CHLOROPHENYL)ETHANOL

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• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

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• Dayang Chem (Hangzhou) Co.,Ltd.
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• (R)-2-chloro-1-(4-chlorophenyl)ethanol

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• SHANGHAI T&W PHARMACEUTICAL CO., LTD.
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• Benzenemethanol,3-chloro-a-(chloromethyl)-, (aR)-

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• Hangzhou J&H Chemical Co., Ltd.
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• (R)-2-chloro-1-(3-chlorophenyl)ethano

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• Xiamen Jenny Chemical Technology Co., Ltd.
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• Benzenemethanol,3-chloro-a-(chloromethyl)-, (aR)-

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• Shandong Mopai Biotechnology Co., LTD
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• (R)-1-(3-Chlorophenyl)-2-chloroethanol

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• Suzhou Health Chemicals Co., Ltd.
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• Benzenemethanol,3-chloro-a-(chloromethyl)-, (aR)-

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• (R)-2-chloro-1-(3-chlorophenyl)ethano CAS No.142763-10-8

  Cas No: 142763-10-8

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• Guangdong Juda Chemical Industrial Co.,Limited
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• (R)-2-CHLORO-1-(3-CHLOROPHENYL)ETHANOLCAS

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142763-10-8 Usage

Uses

(R)-2-chloro-1-(3-chlorophenyl)ethanol is used in the preparation of benzimidazolyl pyridinones as IGF kinase inhibitors.

Check Digit Verification of cas no

The CAS Registry Mumber 142763-10-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,7,6 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 142763-10:
(8*1)+(7*4)+(6*2)+(5*7)+(4*6)+(3*3)+(2*1)+(1*0)=118
118 % 10 = 8
So 142763-10-8 is a valid CAS Registry Number.

InChI:InChI=1/C8H8Cl2O/c9-5-8(11)6-2-1-3-7(10)4-6/h1-4,8,11H,5H2/t8-/m0/s1

142763-10-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	(1R)-2-chloro-1-(3-chlorophenyl)ethanol

1.2 Other means of identification

Product number	-
Other names	2-chloro-1-(3'-chlorophenyl)ethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:142763-10-8 SDS

142763-10-8Upstream product

• 21886-56-6 3-chlorophenacyl chloride 
• 106262-93-5 (+)-2-chloro-1-(3-chlorophenyl)ethanol 
• 84553-19-5 m-(2-Chlorethinyl)-chlorbenzol 
• 108-05-4 vinyl acetate 
• 20697-04-5 3-chlorostyrene oxide 
• 99-02-5 3'-Chloroacetophenone 

142763-10-8Downstream Products

• 166256-69-5 (R)-1-(3-chlorophenyl)-1-hydroxy-2-iodoethane 
• 138908-40-4 CL 316243 
• 139013-14-2 5-{(R)-2-[(R)-5-(3-Chloro-phenyl)-2-oxo-oxazolidin-3-yl]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid diethyl ester 
• 138908-58-4 [R-(R*,R*)]-5-(3-chlorophenyl)-3-[2-(3,4-dimethoxylphenyl)-1-methyl-ethyl]-oxazolidin-2-one 
• 142796-56-3 (R)-5-(3-Chloro-phenyl)-3-[(R)-2-(3,4-dihydroxy-phenyl)-1-methyl-ethyl]-oxazolidin-2-one 
• 142796-55-2 (R)-1-(3-Chloro-phenyl)-2-[(R)-2-(3,4-dimethoxy-phenyl)-1-methyl-ethylamino]-ethanol 
• 169032-01-3 (1R)-2-amino-1-(3-chloro-phenyl)-ethanol hydrochloride 
• 20697-04-5 (R)-meta-chlorostyrene oxide 

142763-10-8Relevant articles and documents

Unmasking the Hidden Carbonyl Group Using Gold(I) Catalysts and Alcohol Dehydrogenases: Design of a Thermodynamically-Driven Cascade toward Optically Active Halohydrins

Escot, Lorena,González-Granda, Sergio,Gotor-Fernández, Vicente,Lavandera, Iván

, p. 2552 - 2560 (2022/02/16)

A concurrent cascade combining the use of a gold(I) N-heterocyclic carbene (NHC) and an alcohol dehydrogenase (ADH) is disclosed for the synthesis of highly valuable enantiopure halohydrins in an aqueous medium and under mild reaction conditions. The meth

Preparation of (R)-2-chloro-1-(m-chlorophenyl)ethanol by Lipozyme TL IM-catalyzed second resolution

Xia, Shi Wen,Lin, Hui,Chen, Yong Zheng

experimental part, p. 289 - 292 (2012/05/05)

(R)-2-Chloro-1-(m-chlorophenyl)ethanol, a precursor of (R)-3-chlorostyrene oxide which is the key chiral intermediate for the preparation of several β3-adrenergic receptor agonists was prepared in 40% yield and 99% ee by the Lipozyme TL IM-catalyzed second resolution of the corresponding racemate in the presence of vinyl acetate.

Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase

Wittman, Mark D.,Balasubramanian, Balu,Stoffan, Karen,Velaparthi, Upender,Liu, Pieying,Krishnanathan, Subramaniam,Carboni, Joan,Li, Aixin,Greer, Ann,Attar, Ricardo,Gottardis, Marco,Chang, Chiehying,Jacobson, Bruce,Sun, Yax,Hansel, Steven,Zoeckler, Mary,Vyas, Dolatrai M.

, p. 974 - 977 (2007/10/03)

A novel class of 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase is described. This report discusses the SAR of 4-(2-hydroxy-2-phenylethylamino)-substituted pyridones with improved IGF-1R potency.

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