142798-22-9 Usage
Molecular weight
257.36 g/mol
Chemical structure
A tetrahydropyridine ring with a cyclopropyl group at position 1 and a phenyl group at position 4
Properties
MPTP is a colorless, odorless, and crystalline solid at room temperature. It is soluble in organic solvents such as methanol and chloroform, but has low solubility in water.
Toxicity
MPTP is a highly toxic chemical compound that selectively damages dopaminergic neurons in the brain, leading to a depletion of dopamine and resulting in Parkinson's disease-like symptoms. It is metabolized into a toxic metabolite known as MPP+, which is responsible for its neurotoxic effects.
Use in research
MPTP is used in scientific research to induce symptoms similar to those of Parkinson's disease in animal models, which has been instrumental in advancing our understanding of the underlying mechanisms of this neurodegenerative disorder and in the development of potential treatments for the condition.
Discovery
MPTP was first synthesized in the 1970s, and its toxic effects were discovered in the 1980s when a group of drug users injected a synthetic form of the compound, leading to severe Parkinson's disease-like symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 142798-22-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,7,9 and 8 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 142798-22:
(8*1)+(7*4)+(6*2)+(5*7)+(4*9)+(3*8)+(2*2)+(1*2)=149
149 % 10 = 9
So 142798-22-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H17N/c1-2-4-12(5-3-1)13-8-10-15(11-9-13)14-6-7-14/h1-5,8,14H,6-7,9-11H2
