142846-71-7 Usage
Description
Galanin-(1-13)-bradykinin-(2-9)-amide is a hybrid neuropeptide composed of the first 13 amino acids of galanin and the last 8 amino acids of bradykinin. Galanin, a 29-amino acid neuropeptide, plays a role in pain modulation, feeding behavior, and hormone secretion regulation, while bradykinin, a nine-amino acid peptide, is involved in inflammation, pain perception, and blood pressure regulation. The combination of these two peptides in Galanin-(1-13)-bradykinin-(2-9)-amide may offer potential therapeutic benefits in managing pain and inflammation through their synergistic effects on modulating pain perception and inflammatory responses.
Uses
Used in Pharmaceutical Industry:
Galanin-(1-13)-bradykinin-(2-9)-amide is used as a potential therapeutic agent for the treatment of pain and inflammation. Its dual action on pain modulation and inflammation regulation makes it a promising candidate for developing new drugs to alleviate chronic pain and inflammatory conditions.
Used in Research Applications:
Galanin-(1-13)-bradykinin-(2-9)-amide serves as a valuable research tool for studying the mechanisms of pain perception and inflammation. By investigating the compound's effects on galanin and bradykinin receptors, researchers can gain insights into the underlying pathways and develop targeted therapies for pain and inflammatory disorders.
Further research is necessary to fully understand the potential benefits, mechanisms of action, and safety profile of Galanin-(1-13)-bradykinin-(2-9)-amide. This will help in optimizing its therapeutic potential and exploring its applications in various medical and pharmaceutical settings.
Check Digit Verification of cas no
The CAS Registry Mumber 142846-71-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,8,4 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 142846-71:
(8*1)+(7*4)+(6*2)+(5*8)+(4*4)+(3*6)+(2*7)+(1*1)=137
137 % 10 = 7
So 142846-71-7 is a valid CAS Registry Number.
InChI:InChI=1/C107H153N27O26/c1-57(2)42-70(123-93(147)71(43-58(3)4)124-95(149)74(47-64-33-35-66(138)36-34-64)121-86(141)52-115-91(145)60(7)118-100(154)78(55-135)128-98(152)77(49-84(109)139)125-94(148)72(44-59(5)6)127-103(157)89(61(8)137)130-99(153)76(119-85(140)50-108)48-65-51-114-68-27-16-15-26-67(65)68)92(146)117-54-88(143)131-38-20-31-82(131)105(159)134-41-21-32-83(134)106(160)133-40-18-29-80(133)101(155)116-53-87(142)120-73(45-62-22-11-9-12-23-62)96(150)129-79(56-136)104(158)132-39-19-30-81(132)102(156)126-75(46-63-24-13-10-14-25-63)97(151)122-69(90(110)144)28-17-37-113-107(111)112/h9-16,22-27,33-36,51,57-61,69-83,89,114,135-138H,17-21,28-32,37-50,52-56,108H2,1-8H3,(H2,109,139)(H2,110,144)(H,115,145)(H,116,155)(H,117,146)(H,118,154)(H,119,140)(H,120,142)(H,121,141)(H,122,151)(H,123,147)(H,124,149)(H,125,148)(H,126,156)(H,127,157)(H,128,152)(H,129,150)(H,130,153)(H4,111,112,113)/t60-,61+,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,89-/m0/s1