142852-50-4 Usage
Description
ZANAPEZIL, also known as an acetylcholinesterase inhibitor, is a pharmaceutical compound with potential applications in the treatment of Alzheimer's disease. It functions by inhibiting the enzyme acetylcholinesterase, which is responsible for the breakdown of the neurotransmitter acetylcholine. By doing so, ZANAPEZIL helps to increase the levels of acetylcholine in the brain, potentially improving cognitive function and memory in patients with Alzheimer's disease.
Uses
Used in Pharmaceutical Industry:
ZANAPEZIL is used as a therapeutic agent for the treatment of Alzheimer's disease. It is particularly effective in managing the cognitive decline and memory impairment associated with the condition by increasing the levels of acetylcholine in the brain, thus potentially improving cognitive function and memory.
Check Digit Verification of cas no
The CAS Registry Mumber 142852-50-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,8,5 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 142852-50:
(8*1)+(7*4)+(6*2)+(5*8)+(4*5)+(3*2)+(2*5)+(1*0)=124
124 % 10 = 4
So 142852-50-4 is a valid CAS Registry Number.
InChI:InChI=1/C25H32N2O/c28-25(23-11-10-22-8-4-5-15-26-24(22)18-23)12-9-20-13-16-27(17-14-20)19-21-6-2-1-3-7-21/h1-3,6-7,10-11,18,20,26H,4-5,8-9,12-17,19H2
142852-50-4Relevant articles and documents
Direct β-Alkylation of Ketones and Aldehydes via Pd-Catalyzed Redox Cascade
Wang, Chengpeng,Dong, Guangbin
, p. 6057 - 6061 (2018/05/14)
We report a direct β-alkylation of ketones and aldehydes with simple alkyl bromides through a Pd-catalyzed redox-cascade strategy. The use of a Cu cocatalyst is important for improved efficiency. The reaction is redox-neutral, without the need for strong acids or bases. Both cyclic and acyclic ketones, as well as α-branched aldehydes, are suitable substrates for coupling with secondary and tertiary alkyl bromides. Concise formal synthesis of Zanapezil is achieved using this β-alkylation method.
