143-81-7

• 

• Basic information

  1. Product Name: sodium 5-(sec-butyl)-5-ethylbarbiturate
  2. Synonyms: sodium 5-(sec-butyl)-5-ethylbarbiturate;Secbutobarbitone sodium;Sodium butabarbital;BUTABARBITAL SODIUM SALT;Asturidon;Bubarbital sodium;Bubartal;Prelital
  3. CAS NO:143-81-7
  4. Molecular Formula: C10H14N2Na2O3
  5. Molecular Weight: 256.2093
  6. EINECS: 205-611-8
  7. Product Categories: API's
  8. Mol File: 143-81-7.mol
  9. Article Data: 0

• Chemical Properties

  1. Melting Point: The free acid mp 165-168°
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: sodium 5-(sec-butyl)-5-ethylbarbiturate(CAS DataBase Reference)
  10. NIST Chemistry Reference: sodium 5-(sec-butyl)-5-ethylbarbiturate(143-81-7)
  11. EPA Substance Registry System: sodium 5-(sec-butyl)-5-ethylbarbiturate(143-81-7)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. RIDADR: 3249
  5. WGK Germany:
  6. RTECS:
  7. HazardClass: 6.1(b)
  8. PackingGroup: III
  9. Hazardous Substances Data: 143-81-7(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products

143-81-7 Suppliers

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143-81-7 Usage

Originator

Butisol sodium,Wallace Labs,USA

Uses

Sedative-hypnotic.

Manufacturing Process

5-sec-Butyl-5-ethylbarbituric acid was prepared from diethyl ester of malonic acid in 3 steps. At the above malonic ester was reacted with C2H5Br and sodium ethylate producing the diethyl ester of ethylmalonic acid, which after a reaction with sodium ethylate and 2-butylbromide gave the ethyl-(2-butyl)- malonic acid diethyl ester. The last one produced the 5-sec-butyl-5-ethylbarbituric acid after a reaction with urea and sodium ethylate. 23 g sodium (1 mol) was dissolved in 300 ml alcohol. To this solution was added a solution of 5-sec-butyl-5-ethyl-barbituric acid (1 mol) in 800 ml alcohol. To a mixture was added 1000 ml benzene, which precipitated the sodium salt of the barbituric acid (butabarbital sodium). The product was filtered and dried.

Therapeutic Function

Hypnotic

Check Digit Verification of cas no

The CAS Registry Mumber 143-81-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 143-81:
(5*1)+(4*4)+(3*3)+(2*8)+(1*1)=47
47 % 10 = 7
So 143-81-7 is a valid CAS Registry Number.

InChI:InChI=1/C10H16N2O3.Na/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14;/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15);/q;+1

143-81-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	sodium,5-butan-2-yl-5-ethyl-4,6-dioxo-1H-pyrimidin-2-olate

1.2 Other means of identification

Product number	-
Other names	Asturidon

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:143-81-7 SDS

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