14316-81-5 Usage
Physical state
Colorless liquid
Odor
Strong, pungent
Uses
Reactive intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds; building block for the production of various fluorinated organic compounds; reagent in the manufacturing of fluorinated polymers and specialty chemicals
Safety precautions
Can cause irritation to the eyes, skin, and respiratory system (handle with caution)
Check Digit Verification of cas no
The CAS Registry Mumber 14316-81-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,1 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 14316-81:
(7*1)+(6*4)+(5*3)+(4*1)+(3*6)+(2*8)+(1*1)=85
85 % 10 = 5
So 14316-81-5 is a valid CAS Registry Number.
14316-81-5Relevant articles and documents
Synthesis and anticancer activity of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and N-bis(trifluoromethyl)alkyl-N′-benzothiazolyl ureas
Luzina, Elena L.,Popov, Anatoliy V.
, p. 4944 - 4953 (2009)
A number of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and -benzothiazolyl ureas have been synthesized and evaluated for their in vitro antiproliferative activities against the human cancer cell lines at the National Cancer Institute (NCI, USA). The activity was shown for compounds 8a,c and 9a-c. The most sensitive cell lines relative to the tested compounds are: 8c PC-3 (prostate cancer, log GI50 -7.10), 9c SNB-75 (CNS cancer, log GI50 -5.84), 9b UO-31 (renal cancer, log GI50 -5.66), and SR (leukemia, log GI50 -5.44) human cancer cells.
